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April 26, 1890

MEDICAL PROGRESS.

JAMA. 1890;XIV(17):611-612. doi:10.1001/jama.1890.02410170019003

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Abstract

Lead Poisoning.  Binet and Prévost have communicated to the Medical Society of Geneva the results of some very interesting researches on the subject of lead poisoning. Their conclusions are these: Animals poisoned by the daily ingestion of white lead presented the following symptoms: A progressive emaciation; anæmia from diminution and alteration of the blood globules, without leucocytosis; albuminuria, which, however, has been neither abundant nor constant; nervous phenomena—paralysis, aphonia, loss of reflexes, anæsthesia, rarely convulsions; the paralyses are curable when the lead is discontinued.The anatomical features are these: A constant alteration of the kidneys, which become grayish, contracted, often cystic; nephritis and a special form of calcareous granulation, according with the type described by Charcot and Gombaut; fatty degeneration of the liver; frequently pericarditis and sometimes granulo-fatty degeneration of the myocardium; lesions of the peripheral nerves of the segmentary type; the medullary roots are rarely affected; regeneration of

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