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June 21, 1890

TROPHO-NEUROSIS OF THE ORAL CAVITY, WITH ESPECIAL REFERENCE TO SYPHILITIC NECROSIS.Read in the Section of Dental and Oral Surgery at the Forty-first Annual Meeting of the American Medical Association at Nashville, Tenn., May 22, 1890.

JAMA. 1890;XIV(25):889-893. doi:10.1001/jama.1890.02410250009001c

At the meeting of the Southern Surgical and Gynæcological Association held in Nashville, November, 1889, I had the pleasure of presenting certain views regarding the relation of trophoneurosis to the phenomena of syphilis. In that essay I endeavored to show the dependence of every phenomenon characteristic of syphilis upon certain more or less obscure changes in the sympathetic nervous system (organic or functional, temporary or permanent), which resulted in aberrations of its trophic function. The more thoroughly I studied the phenomena of syphilis, the more firmly convinced I became not only of the dependence of syphilitic phenomena, but that of many other morbid changes which have hitherto appeared inexplicable, upon tropho-neuroses.

In a general way it may be said that disease affecting the animal body can only be produced by one of two things, viz.: (1) Perversion in the quality or quantity of the nutritive material which constitutes the pabulum