C. H. Hughes, M.D., Dear Friend:—I have been much interested in your article, published in The Journal of February 27, 1892, on "Influenza as a Neurotic Disease."
Since my first experience with the disease in the winter of 1889-90, I have regarded it as one of depression of the nerve centers, anœmia of the ultimate brain cells, as I conceive it. That the disease dates from the onset of fever and chill, or influenza, I am and ever have been seriously at a doubt. Patients marked out for such phenomena are for weeks prior to such attacks the subjects of langour and paleness, of countenance. Many of the cases in this locality have almost entirely escaped fever and rigor, a few having little or no cough, all more or less suffering from neuralgia about the head or face, mostly, as they express it, a pain in the back of the
LINK JE. LA GRIPPE. JAMA. 1892;XIX(4):90–95. doi:10.1001/jama.1892.02420040002001a
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