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July 30, 1892

Incompatible with Antipyrine.

JAMA. 1892;XIX(5):145. doi:10.1001/jama.1892.02420050027008

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—The salicylate of sodium and antipyrine form a mixture from which an oily substance separates. The same is true of chloral hydrate. With beta-naphthol, antipyrine becomes hygroscopic. These changes take place when dry trituration of the respective substances is undertaken.

The quotation, "Who shall decide when doctors disagree and soundest casuists doubt like you and me," was written by Alexander Pope, Moral Essays, Epistle 3, line 1. The original did not apply to doctors of medicine, but to doctors of philosophy. Yours, J. B. H.

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