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August 6, 1892

EUROPHEN, WITH CLINICAL REFERENCE TO EUROPHEN AND EUROPHEN-ARISTOL.Read by title in the Section of Practice of Medicine at the Forty-third Annual Meeting of the American Medical Association, he.ld at Detroit, Mich., June, 1892.

Author Affiliations


JAMA. 1892;XIX(6):151-155. doi:10.1001/jama.1892.02420060005001a

Europhen results from the action of iodine upon isobutylorthocresol in a solution of iodine of potassium. The product, as prepared and sent out by the Farbenfabriken, formerly Friedrich Bayer & Co., of Elberfeld, appears in the form of a fine, soft amorphous powder, slightly resinous to the touch, of a light yellow color, destitute of taste and having a faint, not unpleasant odor which recalls that of saffron. This odor is almost entirely lost when europhen is made into a mixture or solution. Europhen is insoluble in water and glycerine, soluble in alcohol, ether, chloroform and fixed oils. When exposed to a heat of 160° F.,europhen thickens and at 230° F.,is converted into a clear brown fluid. The specific gravity of europhen is five times less than that of iodoform and half that of iodol. The body is easily decomposed by light and heat. It should, therefore, be kept in

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