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August 27, 1892


JAMA. 1892;XIX(9):239-240. doi:10.1001/jama.1892.02420090001001

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THE POWERFUL EFFECT OF SULFONAL IN ARRESTING THE CRAMPS OF FRACTURED LIMBS, AND REFLEX SPASMS FROM OTHER CAUSES.  Read before the Section of Surgery and Anatomy, at the Forty-third Annual Meeting of the American Medical Association, at Detroit, Mich., June, 1892.BY EDWARD ANDREWS, M.D., OF CHICAGO.Sulfonal was discovered only six years ago by E. Baumann. Chemical nomenclature has evolved for it the frightful name of diethyl sulphon—dimethyl—methan. Prof. A. Kast first reported on its qualities in Die Berliner Klin. Wochenschrift, in 1888, or four years ago. About three years ago my attention was turned to its remarkable power of arresting the spasms of fractured limbs by having given a dose for its supposed hypnotic effect, and finding instead a strong antispasmodic result. I published my observation not long afterwards in a short article. Since then I have continued my experiments, and now offer a condensed statement of

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