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November 26, 1892

THE ANTITOXIC PROPERTIES OF THE BLOOD OF CHOLERA CONVALESCENTS.

JAMA. 1892;XIX(22):647. doi:10.1001/jama.1892.02420220025010

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Abstract

The researches of Klemperer (The Journal Oct. 29,) have shown, that while the blood serum of normal men possesses either no influence or but a very feeble one upon the toxicity of cultures of cholera bacilli a decided antitoxic effect is exerted by the blood of people who have been inoculated with cholera bacilli subcutaneously. The antitoxic effect of the blood serum of patients recovered from genuine cholera has now been tested by Lazarus of Berlin, Berliner klin. Wochenschrift, Nos. 43 and 44,with remarkable results.

Our conception of the term immunity has gained in precision very much since clinical observations have been supplemented by laboratory work. From the earlier researches of Pasteur on anthrax and chicken cholera it became evident that there may be different degrees of immunity. After Behring had discovered that an important—if not the most important factor in acquired immunity is the acquired antitoxic property of the

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