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December 17, 1892


JAMA. 1892;XIX(25):729-730. doi:10.1001/jama.1892.02420250023003

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That certain forms of albuminuria may exist without disease of the kidneys, or, at least, without a primary affection of these organs, is a well established clinical observation; but the fact that, as a rule, such cases afford a favorable prognosis is not generally accepted. Without including unavoidable albuminuria, where the presence of blood or pus in the urine fully accounts for the existence of the albumen; nor febrile albuminuria, where the albumen is clearly the result of elevation of bodily temperature, or disturbance of circulation in the kidneys, we have remaining for consideration a well-marked group of cases in which albuminuria has its origin or immediate cause in some alteration, either transitory or more or less permanent, in the composition of the blood. Fothergill, in his monograph on " Vaso-renal Change versus Bright's Disease," summed up the evidence in support of his favorite view that the presence of an excess

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