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Article
December 17, 1892

REGENERATION OF MUSCLE.

JAMA. 1892;XIX(25):731-732. doi:10.1001/jama.1892.02420250025005

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Abstract

Rudolph Volkmann has recently made an extensive study of the processes that result in regeneration of striated muscular tissue as shown in the skeletal muscles after typhoid fever, after the influence of very low temperature, in trichiniasis, and after injuries, actual and experimental. Among the results of his studies may be mentioned that in striped muscle the regenerative changes commence in the nuclei of old fibres with which the new elements may, or may not, remain connected. In the first instance the process corresponds to the formation of buds, as described by Neumann, while the development of new elements without direct connection with the preexisting resembles the embryonal type of muscle growth. In both forms the proliferation of muscle nuclei and the growth of protoplasm around them form the beginning of regeneration and in both forms, which may go on side by side, the protoplasm early shows a fine fibrillar

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