July 5, 2022, Vol 328, No. 1, Pages 3-84

In This Issue of JAMA

Audio Highlights

Abstract Full Text

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JAMA. 2022;328(1):e2117034. doi:10.1001/jama.2021.17034

Audio Editors' Summary: Nurse Home Visits and Birth Outcomes, Cardiopulmonary Bypass in Children Undergoing Heart Surgery, Peanut Allergy After Early Introduction of Peanut in Infants, and more

Original Investigation

Effect of an Intensive Nurse Home Visiting Program on Adverse Birth Outcomes in a Medicaid-Eligible Population: A Randomized Clinical Trial

Margaret A. McConnell, PhD; Slawa Rokicki, PhD; Samuel Ayers, BA; et al.

Abstract Full Text

JAMA. 2022;328(1):27-37. doi:10.1001/jama.2022.9703

This randomized clinical trial assesses the effect of an intensive nurse home visiting program on a composite outcome of preterm birth, low birth weight, small for gestational age, or perinatal mortality among Medicaid-eligible, nulliparous pregnant individuals at less than 28 weeks’ gestation in South Carolina.

Editorial
Intensive Nurse Home Visiting Program and Adverse Birth Outcomes
Michelle H. Moniz, MD, MSc; Lisa Kane Low, PhD, CNM; Molly J. Stout, MD, MS

Caring for the Critically Ill Patient

Effect of Nitric Oxide via Cardiopulmonary Bypass on Ventilator-Free Days in Young Children Undergoing Congenital Heart Disease Surgery: The NITRIC Randomized Clinical Trial

Luregn J. Schlapbach, MD, PhD; Kristen S. Gibbons, PhD; Stephen B. Horton, PhD; et al.

Abstract Full Text

JAMA. 2022;328(1):38-47. doi:10.1001/jama.2022.9376

This clinical trial compares the efficacy of nitric oxide applied into the cardiopulmonary bypass oxygenator vs standard care on ventilator-free days in children younger than 2 years undergoing surgery for congenital heart disease.

Association Between Earlier Introduction of Peanut and Prevalence of Peanut Allergy in Infants in Australia

Victoria X. Soriano, PhD; Rachel L. Peters, PhD; Margarita Moreno-Betancur, PhD; et al.

Abstract Full Text

JAMA. 2022;328(1):48-56. doi:10.1001/jama.2022.9224

This cross-sectional study examines the change in prevalence of peanut allergy after the introduction of guidelines recommending early peanut introduction for all infants, in both the general population and in predetermined subgroups of high-risk infants, in Australia.

Editorial
Can Peanut Allergy Prevention Be Translated to the Pediatric Population?
Jennifer Dantzer, MD, MHS; Robert A. Wood, MD

Research Letter

Neurodevelopment at 5 Years of Age According to Early Screening for Patent Ductus Arteriosus in Extremely Preterm Infants

Gilles Cambonie, MD, PhD; Jean-Christophe Rozé, MD, PhD; Laetitia Marchand-Martin, MS; et al.

Abstract Full Text

JAMA. 2022;328(1):71-73. doi:10.1001/jama.2022.6812

This study compares neurodevelopment at 5 years of age in children who were extremely preterm infants and who underwent early systematic echocardiographic screening for patent ductus arteriosus (PDA) vs those who did not undergo screening.

Excess Mortality in Massachusetts During the Delta and Omicron Waves of COVID-19

Jeremy Samuel Faust, MD, MS; Chengan Du, PhD; Chenxue Liang, MS, MPH; et al.

Abstract Full Text

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JAMA. 2022;328(1):74-76. doi:10.1001/jama.2022.8045

This modeling study estimates the excess deaths attributable to COVID-19 disease in Massachusetts during the Delta (June to December 2021) and Omicron (December 2021 to February 2022) waves.

Viewpoint

The Leaked Supreme Court Ruling Opinion: Implications for Abortion Access

Rebecca B. Reingold, JD; Lawrence O. Gostin, JD

Abstract Full Text

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JAMA. 2022;328(1):13-14. doi:10.1001/jama.2022.10204

This Viewpoint examines the ramifications of the US Supreme Court overturning Roe v Wade, including limitations on abortion access, legal consequences, financial consequences, and the erosion of personal rights particularly for marginalized and underserved populations.

What Overturning Roe v Wade May Mean for Assisted Reproductive Technologies in the US

I. Glenn Cohen, JD; Judith Daar, JD; Eli Y. Adashi, MD, MS

Abstract Full Text

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JAMA. 2022;328(1):15-16. doi:10.1001/jama.2022.10163

This Viewpoint discusses the potential ramifications for assisted reproductive technologies, such as in vitro fertilization, if the Supreme Court overturns Roe v Wade.

The Role of Health Care Systems in Bolstering the Social Safety Net to Address Health Inequities in the Wake of the COVID-19 Pandemic

Rita Hamad, MD, PhD; Sandro Galea, MD, DrPH

Abstract Full Text

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JAMA. 2022;328(1):17-18. doi:10.1001/jama.2022.10160

This Viewpoint discusses how relying almost exclusively on health care systems to address overall health in the US is problematic, noting that safety net programs and other social policies can serve as powerful population-level interventions that can affect long-standing health disparities.

A Piece of My Mind

The True Cause of Death

Carla M. Perissinotto, MD, MHS

Abstract Full Text

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JAMA. 2022;328(1):19-20. doi:10.1001/jama.2022.10406

In this narrative medicine essay, a palliative care physician contemplates how including life circumstances—social isolation or systemic racism—on death certificates as contributing factors to death is one way of informing policy decisions.

Editorial

The Urgency of Now and the Responsibility to Do More—My Commitment for JAMA and the JAMA Network

Kirsten Bibbins-Domingo, PhD, MD, MAS

Abstract Full Text

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JAMA. 2022;328(1):21-22. doi:10.1001/jama.2022.11108

Audio Author Interview: A Conversation With Dr Kirsten Bibbins-Domingo, JAMA’s New Editor in Chief

Intensive Nurse Home Visiting Program and Adverse Birth Outcomes

Michelle H. Moniz, MD, MSc; Lisa Kane Low, PhD, CNM; Molly J. Stout, MD, MS

Abstract Full Text

JAMA. 2022;328(1):23-24. doi:10.1001/jama.2022.9162

Can Peanut Allergy Prevention Be Translated to the Pediatric Population?

Jennifer Dantzer, MD, MHS; Robert A. Wood, MD

Abstract Full Text

JAMA. 2022;328(1):25-26. doi:10.1001/jama.2022.6263

Review

Sickle Cell Disease: A Review

Patricia L. Kavanagh, MD; Titilope A. Fasipe, MD, PhD; Ted Wun, MD

Abstract Full Text

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JAMA. 2022;328(1):57-68. doi:10.1001/jama.2022.10233

This Review summarizes the pathophysiology and diagnosis for sickle cell disease (SCD), management for SCD and its related complications, and prognosis for patients with SCD.

Audio Clinical Review: Sickle Cell Disease

JAMA Insights

Clinical Update

Diagnosis and Treatment of Combined Pulmonary Fibrosis and Emphysema in 2022

Masahiro Nemoto, MD; Chi Wan Koo, MD; Jay H. Ryu, MD

Abstract Full Text

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JAMA. 2022;328(1):69-70. doi:10.1001/jama.2022.8492

This JAMA Insights Clinical Update discusses the diagnosis, prognosis, and treatment of combined pulmonary fibrosis and emphysema, which is likely underestimated and underreported.

Medical News & Perspectives

WHO: Pandemic Sparked a Push for Global Mental Health Transformation

Bridget M. Kuehn, MSJ

Abstract Full Text

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JAMA. 2022;328(1):5-7. doi:10.1001/jama.2022.10241

This Medical News article discusses a new report from the World Health Organization that calls for a transformation of global mental health care focused on human rights and community-based prevention and care.