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December 6, 2022, Vol 328, No. 21, Pages 2085-2170

In This Issue of JAMA

Audio Highlights

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JAMA. 2022;328(21):e2117234. doi:10.1001/jama.2021.17234
Original Investigation

Effect of Timing by Endometrial Receptivity Testing vs Standard Timing of Frozen Embryo Transfer on Live Birth in Patients Undergoing In Vitro Fertilization: A Randomized Clinical Trial

Abstract Full Text
JAMA. 2022;328(21):2117-2125. doi:10.1001/jama.2022.20438

This randomized clinical trial compares the efficacy of frozen embryo transfer (FET) timed according to endometrial receptivity testing vs standardized frozen embryo transfer in improving live birth rate.

Association of Medicare Advantage vs Traditional Medicare With 30-Day Mortality Among Patients With Acute Myocardial Infarction

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JAMA. 2022;328(21):2126-2135. doi:10.1001/jama.2022.20982

This retrospective cohort study compares 30-day mortality rates between patients with acute myocardial infarction who are insured by Medicare Advantage vs traditional Medicare.

Association Between Individual Primary Care Physician Merit-based Incentive Payment System Score and Measures of Process and Patient Outcomes

Abstract Full Text
JAMA. 2022;328(21):2136-2146. doi:10.1001/jama.2022.20619

This cross-sectional study of US primary care physicians participating in the Medicare Merit-based Incentive Payment System (MIPS) program in 2019 examines whether primary care physicians’ MIPS scores are associated with performance on process and outcome measures.

Research Letter

US Trends in Drug Overdose Mortality Among Pregnant and Postpartum Persons, 2017-2020

Abstract Full Text
JAMA. 2022;328(21):2159-2161. doi:10.1001/jama.2022.17045

This study evaluates changes in overall and drug-specific overdose mortality among pregnant and postpartum persons before and during the COVID-19 pandemic.

Premiums and Out-of-Pocket Spending for Long-acting Insulins Under the Medicare Part D Senior Savings Model

Abstract Full Text
JAMA. 2022;328(21):2161-2162. doi:10.1001/jama.2022.17232

This study uses data from January/Q1 2022 Medicare Prescription Drug Plan Formulary files to compare premiums and total spending for users of long-acting insulin who selected prescription drug plans in 2022 and to estimate potential savings for beneficiaries who selected Senior Savings model-participating plans.

Viewpoint

Medicaid’s Moment for Protecting and Promoting Women’s Health

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JAMA. 2022;328(21):2105-2106. doi:10.1001/jama.2022.21048

This Viewpoint examines pathways that advocates, policy makers, states, and Medicaid agencies can take to identify opportunities for state Medicaid agencies to protect and promote perinatal health.

Medicare 2.0—A Vision for the Future of America’s Health Insurance Plan

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JAMA. 2022;328(21):2107-2108. doi:10.1001/jama.2022.22092

This Viewpoint offers recommendations to unify various Medicare reform proposals to optimize the health insurance plan.

An Innovation Surcharge to Fund the Repurposing of Generic Drugs

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JAMA. 2022;328(21):2109-2110. doi:10.1001/jama.2022.21250

This Viewpoint discusses the market for generic drugs and an innovation surcharge that would be awarded to public entities, such as the National Institutes of Health, and its newly formed Advanced Research Projects Agency for Health, to fund research for the repurposing of generic drugs.

A Piece of My Mind

The Club

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JAMA. 2022;328(21):2111. doi:10.1001/jama.2022.21302

In this narrative medicine essay, an internal medicine physician traveling a lonely road of grief over the loss of her son finds a bond among the many patients who also lost a child.

Editorial

How Much of an “Advantage” Is Medicare Advantage?

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JAMA. 2022;328(21):2112-2113. doi:10.1001/jama.2022.21892

Pay for Performance: When Slogans Overtake Science in Health Policy

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JAMA. 2022;328(21):2114-2116. doi:10.1001/jama.2022.20945
Review

Progress and Challenges in Bacterial Meningitis: A Review

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JAMA. 2022;328(21):2147-2154. doi:10.1001/jama.2022.20521

This review summarizes current evidence on the epidemiology, diagnosis, and treatment of bacterial meningitis.

JAMA Guide to Statistics and Methods

Adjustment for Baseline Characteristics in Randomized Clinical Trials

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JAMA. 2022;328(21):2155-2156. doi:10.1001/jama.2022.21506

This Guide to Statistics and Methods provides an overview of the use of adjustment for baseline characteristics in the analysis of randomized clinical trials and emphasizes several important considerations.

JAMA Diagnostic Test Interpretation

Peritoneal Fluid Analysis in Peritoneal Dialysis–Associated Peritonitis

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JAMA. 2022;328(21):2157-2158. doi:10.1001/jama.2022.21289

A 62-year-old woman undergoing peritoneal dialysis (PD) presented to the clinic with severe abdominal pain and cloudy PD fluid. Seven days prior, she inadvertently broke aseptic technique when tightening a leaking connection of her PD catheter tubing. Cloudy fluid that was drained from her PD catheter was sent for laboratory analysis. What would you do next?

Medical News & Perspectives

Highlights From Infectious Disease Week 2022—COVID-19, HIV, Monkeypox, and Polio

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JAMA. 2022;328(21):2089-2091. doi:10.1001/jama.2022.17754

This Medical News article explores timely topics discussed at the annual IDWeek conference.

How Immune-Evasive Omicron Offspring and a Lack of Mitigation Measures Could Shape a COVID-19 Winter Wave

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JAMA. 2022;328(21):2092-2095. doi:10.1001/jama.2022.17758

This Medical News feature examines what the COVID-19 pandemic might look like this winter.

“This Is Our COVID”—What Physicians Need to Know About the Pediatric RSV Surge

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JAMA. 2022;328(21):2096-2098. doi:10.1001/jama.2022.21638

This Medical News article discusses an out-of-season increase in respiratory syncytial virus, influenza, and other respiratory infections that is severely straining the pediatric health care system.

News From the JAMA Network

Losartan Decreases Incidence of Epilepsy in Arterial Hypertension

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JAMA. 2022;328(21):2099. doi:10.1001/jama.2022.20025

Short Life Expectancy No Deterrent to Cancer Screening for Some Physicians

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JAMA. 2022;328(21):2099. doi:10.1001/jama.2022.20024

Long-term Intensive Blood Pressure Control Hard to Maintain

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JAMA. 2022;328(21):2099-2100. doi:10.1001/jama.2022.20026

Group Recommends Clinical Instruments to Measure Atopic Eczema Burden

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JAMA. 2022;328(21):2100. doi:10.1001/jama.2022.20027
News From the Food and Drug Administration

FDA Approves Artificial Intelligence Device for Guiding Regional Anesthesia

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JAMA. 2022;328(21):2101. doi:10.1001/jama.2022.20029

Novavax COVID-19 Vaccine Booster Authorized

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JAMA. 2022;328(21):2101. doi:10.1001/jama.2022.20028

Cooling Device to Prevent Chemotherapy Oral Mucositis Gains Authorization

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JAMA. 2022;328(21):2101. doi:10.1001/jama.2022.20030

Final Results for Study of Transvaginal Mesh for Pelvic Organ Prolapse

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JAMA. 2022;328(21):2101-2102. doi:10.1001/jama.2022.22134
Poetry and Medicine

Wisecrack

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JAMA. 2022;328(21):2166. doi:10.1001/jama.2022.21119
JAMA Revisited

Foreign Letters: London

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JAMA. 2022;328(21):2167. doi:10.1001/jama.2021.17235
JAMA Patient Page

Bacterial Meningitis

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JAMA. 2022;328(21):2170. doi:10.1001/jama.2022.21603

This JAMA Patient Page explains the symptoms, spread, diagnosis, treatment, and prevention of bacterial meningitis, an infection that causes inflammation of the tissues surrounding the brain and spinal cord.

Comment & Response

SARS-CoV-2 Reduction in Shared Indoor Air

Abstract Full Text
JAMA. 2022;328(21):2162-2163. doi:10.1001/jama.2022.18028

SARS-CoV-2 Reduction in Shared Indoor Air

Abstract Full Text
JAMA. 2022;328(21):2163. doi:10.1001/jama.2022.18025

SARS-CoV-2 Reduction in Shared Indoor Air—Reply

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JAMA. 2022;328(21):2163-2164. doi:10.1001/jama.2022.18031

Association Between COVID-19 Booster Vaccination and Omicron Infection in a Cohort of Players and Staff in the National Basketball Association

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JAMA. 2022;328(21):2164-2165. doi:10.1001/jama.2022.18034

Association Between COVID-19 Booster Vaccination and Omicron Infection in a Cohort of Players and Staff in the National Basketball Association—Reply

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JAMA. 2022;328(21):2165. doi:10.1001/jama.2022.18036
JAMA Masthead

JAMA

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JAMA. 2022;328(21):2085-2086. doi:10.1001/jama.2021.17232
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