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September 18, 2018, Vol 320, No. 11, Pages 1083-1210

In This Issue of JAMA

Highlights

Abstract Full Text
free access has audio
JAMA. 2018;320(11):1083-1085. doi:10.1001/jama.2017.12548
  • Audio Summary: Physician Burnout, PET Diagnosis of Alzheimer Disease, Weight Loss Interventions to Prevent Obesity-Related Illness, and more
Viewpoint

On the Prospects for a (Deep) Learning Health Care System

C. David Naylor, MD, DPhil
Abstract Full Text
JAMA. 2018;320(11):1099-1100. doi:10.1001/jama.2018.11103

In this Viewpoint, David Naylor reviews factors driving the adoption of deep learning and artificial intelligence in health care, including the digitization of health data and efficiencies in processing those data sets to automate routine clinical tasks and accelerate research and technology development.

Deep Learning—A Technology With the Potential to Transform Health Care

Geoffrey Hinton, PhD
Abstract Full Text
JAMA. 2018;320(11):1101-1102. doi:10.1001/jama.2018.11100

In this Viewpoint, Geoffrey Hinton of Google’s Brain Team discusses the basics of neural networks: their underlying data structures, how they can be trained and combined to process complex health data sets, and future prospects for harnessing their unsupervised learning to clinical challenges.

Informatics, Data Science, and Artificial Intelligence

Lisha Zhu, PhD; W. Jim Zheng, PhD
Abstract Full Text
JAMA. 2018;320(11):1103-1104. doi:10.1001/jama.2018.8211

This Viewpoint discusses how advances in data science and informatics are driving a transformation of biomedical research and clinical practice toward models where data mining and artificial intelligence will underlie development of precision therapies.

A Piece of My Mind

Silent Space

Ian J. Barbash, MD, MS
Abstract Full Text
free access
JAMA. 2018;320(11):1105-1106. doi:10.1001/jama.2018.12753

In this narrative medicine essay, an intensivist tells how he and his colleagues joined in a moment of silence to honor the ICU death of a man under their care with a do-not-resuscitate order.

Editorial

Clinical Implications and Challenges of Artificial Intelligence and Deep Learning

William W. Stead, MD
Abstract Full Text
JAMA. 2018;320(11):1107-1108. doi:10.1001/jama.2018.11029

Physician Burnout—A Serious Symptom, But of What?

Thomas L. Schwenk, MD; Katherine J. Gold, MD, MSW, MS
Abstract Full Text
JAMA. 2018;320(11):1109-1110. doi:10.1001/jama.2018.11703

Weight Management in Adults With ObesityWhat Is a Primary Care Clinician to Do?

Susan Z. Yanovski, MD
Abstract Full Text
free access
JAMA. 2018;320(11):1111-1113. doi:10.1001/jama.2018.11031
Original Investigation

Association of Clinical Specialty With Symptoms of Burnout and Career Choice Regret Among US Resident Physicians

Liselotte N. Dyrbye, MD, MHPE; Sara E. Burke, PhD; Rachel R. Hardeman, PhD, MPH; et al.
Abstract Full Text
has active quiz
JAMA. 2018;320(11):1114-1130. doi:10.1001/jama.2018.12615

This survey study investigates risk factors for symptoms of burnout and career choice regret among US physicians during their second year of residency.

Prevalence of Burnout Among PhysiciansA Systematic Review

Lisa S. Rotenstein, MD, MBA; Matthew Torre, MD; Marco A. Ramos, MD, PhD; et al.
Abstract Full Text
JAMA. 2018;320(11):1131-1150. doi:10.1001/jama.2018.12777

This systematic review assesses how burnout among practicing physicians has been defined in the published medical literature and estimates its prevalence by definitions, assessment methods, and study quality.

Preliminary Communication

Discriminative Accuracy of [18F]flortaucipir Positron Emission Tomography for Alzheimer Disease vs Other Neurodegenerative Disorders

Rik Ossenkoppele, PhD; Gil D. Rabinovici, MD; Ruben Smith, MD, PhD; et al.
Abstract Full Text
JAMA. 2018;320(11):1151-1162. doi:10.1001/jama.2018.12917

This diagnostic accuracy study characterizes the ability of [18F]flortaucipir to discriminate Alzheimer from non-Alzheimer neurodegenerative disorders among patients at dementia clinics and research centers.

US Preventive Services Task Force

Recommendation Statement

Behavioral Weight Loss Interventions to Prevent Obesity-Related Morbidity and Mortality in AdultsUS Preventive Services Task Force Recommendation Statement

US Preventive Services Task Force
Abstract Full Text
free access has active quiz has audio
JAMA. 2018;320(11):1163-1171. doi:10.1001/jama.2018.13022

This 2018 Recommendation Statement from the US Preventive Services Task Force recommends that clinicians offer or refer adults with a body mass index of 30 or higher to intensive, multicomponent behavioral interventions (B recommendation).

  • Audio Interview: USPSTF Recommendation: Behavioral Interventions to Prevent Adult Obesity-Related Outcomes

Evidence Report

Behavioral and Pharmacotherapy Weight Loss Interventions to Prevent Obesity-Related Morbidity and Mortality in AdultsUpdated Evidence Report and Systematic Review for the US Preventive Services Task Force

Erin S. LeBlanc, MD, MPH; Carrie D. Patnode, PhD, MPH; Elizabeth M. Webber, MS; et al.
Abstract Full Text
free access
JAMA. 2018;320(11):1172-1191. doi:10.1001/jama.2018.7777

This systematic review to support the 2018 US Preventive Services Task Force Recommendation Statement on interventions to prevent obesity-related morbidity and mortality summarizes published evidence on the benefits and harms of behavioral and pharmacotherapy weight loss and weight loss maintenance interventions in adults.

JAMA Guide to Statistics and Methods

On Deep Learning for Medical Image Analysis

Lawrence Carin, PhD; Michael J. Pencina, PhD
Abstract Full Text
has multimedia
JAMA. 2018;320(11):1192-1193. doi:10.1001/jama.2018.13316

This JAMA Guide to Statistics and Methods explains the basic concepts underlying convolutional neural networks (CNNs), a type of machine learning being used to automate the reading of medical images.

Research Letter

Association Between Maintaining Certification in General Surgery and Loss-of-License Actions

Andrew T. Jones, PhD; Jason P. Kopp, PhD; Mark A. Malangoni, MD
Abstract Full Text
JAMA. 2018;320(11):1195-1196. doi:10.1001/jama.2018.9550

This study uses American Board of Surgery data to assess the association between maintainence of certification in general surgery and loss-of-license actions after expiration of the initial 10-year certification among general surgeons.

Scholarship Support for Veterans Enrolling in MD, JD, and MBA Programs

Stephen Graves, MS; Brandon-Luke L. Seagle, MD; Masha Kocherginsky, PhD; et al.
Abstract Full Text
JAMA. 2018;320(11):1197-1198. doi:10.1001/jama.2018.10260

This study compares Veterans Administration (VA) scholarship support for veterans enrolling in degree-granting medical schools vs law or business programs at the same institutions.

Medical News & Perspectives

A Day in the LifeCaring for Transgender Patients in New York City

Jennifer Abbasi
Abstract Full Text
free access
JAMA. 2018;320(11):1092-1093. doi:10.1001/jama.2018.11218

This Medical News article profiles Joshua D. Safer, MD, who leads Mount Sinai’s Center for Transgender Medicine and Surgery.

Are Bacteria Transplants the Future of Eczema Therapy?

Jennifer Abbasi
Abstract Full Text
free access
JAMA. 2018;320(11):1094-1095. doi:10.1001/jama.2018.12334

This Medical News article discusses early clinical trials of beneficial bacteria therapy for eczema, or atopic dermatitis.

News From the Food and Drug Administration

Generic Form of EpiPen Approved

Rebecca Voelker, MSJ
Abstract Full Text
free access
JAMA. 2018;320(11):1098. doi:10.1001/jama.2018.13297

Vaginal Ring Contraceptive Remains Effective for 1 Year

Rebecca Voelker, MSJ
Abstract Full Text
free access
JAMA. 2018;320(11):1098. doi:10.1001/jama.2018.13299

Brain Stimulation Approved for Obsessive-Compulsive Disorder

Rebecca Voelker, MSJ
Abstract Full Text
free access
JAMA. 2018;320(11):1098. doi:10.1001/jama.2018.13301
The JAMA Forum

Enabling School Success to Improve Community Health

Josh Sharfstein, MD; Roberto Santamaria, MPH, MBA
Abstract Full Text
free access
JAMA. 2018;320(11):1096. doi:10.1001/jama.2018.12567
Global Health

Armadillos Bring Risk of Leprosy

M.J. Friedrich
Abstract Full Text
free access
JAMA. 2018;320(11):1097. doi:10.1001/jama.2018.12741

Early Initiation of Breastfeeding

M.J. Friedrich
Abstract Full Text
free access
JAMA. 2018;320(11):1097. doi:10.1001/jama.2018.13372

Cardiovascular Disease in India

M.J. Friedrich
Abstract Full Text
free access
JAMA. 2018;320(11):1097. doi:10.1001/jama.2018.13373
Comment & Response

Premedication for Neonates Requiring Nonemergency Intubation

Frank Fideler, MD; Christian Grasshoff, MD
Abstract Full Text
JAMA. 2018;320(11):1199. doi:10.1001/jama.2018.10014

Premedication for Neonates Requiring Nonemergency Intubation—Reply

Xavier Durrmeyer, MD, PHD; Pierre Tourneux, MD, PhD; Agnes Dechartres, MD, PhD
Abstract Full Text
JAMA. 2018;320(11):1199-1200. doi:10.1001/jama.2018.10025

Safety of Topical Calcineurin Inhibitors for Hailey-Hailey Disease

Fei Han, MS
Abstract Full Text
JAMA. 2018;320(11):1200. doi:10.1001/jama.2018.9554

Safety of Topical Calcineurin Inhibitors for Hailey-Hailey Disease—Reply

Christopher T. Haley, MD; Uyen Ngoc Mui, MD; Stephen K. Tyring, MD, PhD
Abstract Full Text
JAMA. 2018;320(11):1200-1201. doi:10.1001/jama.2018.9558

Treatment of Chronic Hepatitis B Infection

Yi-Hua Zhou, MD, PhD
Abstract Full Text
JAMA. 2018;320(11):1201. doi:10.1001/jama.2018.10007

Treatment of Chronic Hepatitis B Infection—Reply

Lydia Tang, MBChB; Shyam Kottilil, MD, PhD
Abstract Full Text
JAMA. 2018;320(11):1202. doi:10.1001/jama.2018.10021
Correction

Incorrect Expansion of a Term and Other Clarifications

Abstract Full Text
free access
JAMA. 2018;320(11):1202. doi:10.1001/jama.2018.9637
Poetry and Medicine

Spring Downsizing

Ronald  Pies, MD
Abstract Full Text
free access
JAMA. 2018;320(11):1203. doi:10.1001/jama.2018.5762
JAMA Revisited

Proprietaries, Pianos and Probity

Abstract Full Text
JAMA. 2018;320(11):1204. doi:10.1001/jama.2017.12578
JAMA Patient Page

Behavioral Interventions for Weight Loss

Jill Jin, MD, MPH
Abstract Full Text
free access
JAMA. 2018;320(11):1210. doi:10.1001/jama.2018.13125

This JAMA Patient Page describes the US Preventive Services Task Force’s recent recommendations on behavioral interventions for weight loss to prevent obesity-related problems in adults.

JAMA Masthead

JAMA

Abstract Full Text
free access
JAMA. 2018;320(11):1087-1088. doi:10.1001/jama.2017.12549

New Online

Aging as a Biological Target for Prevention and Therapy
Viewpoint | September 17, 2018
Aging, Cell Senescence, and Chronic DiseaseEmerging Therapeutic Strategies
Viewpoint | September 17, 2018
From Lifespan to Healthspan
Viewpoint | September 17, 2018
All New Online
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