This randomized clinical trial compares the effect of different doses (8 mg/d or 16 mg/d) of extended-release morphine vs placebo on chronic breathlessness in people with chronic obstructive pulmonary disease (COPD).
This cross-sectional study compares in-hospital mortality among patients with ST-segment elevation myocardial infarction receiving treatment within the US national guidelines–recommended target times vs later.
This cross-sectional spatial analysis examines travel time from each census tract in the contiguous US to the nearest abortion facility before and after the Dobbs v Jackson Women’s Health Organization US Supreme Court decision.
This study assesses changes in the number of abortions and changes in the percentage of out-of-state abortions among Texas residents performed 12 or more weeks of gestation in the first six 6 months following implementation of a Texas senate bill prohibiting abortions after detection of embryonic cardiac activity.
This study includes clinical laboratories that participated in the first general chemistry proficiency testing survey in 2022 to assess awareness and adoption of new equations from the Chronic Kidney Disease Epidemiology Collaboration for estimated glomerular filtration rate (eGFR) that eliminated race-adjustment factors, including one based on creatinine and one based on creatinine and cystatin C.
This study examines adverse events and durability of response of SER-109, an investigational microbiome therapeutic comprised of purified Firmicutes spores, compared with placebo for Clostridioides difficile infection.
This study uses electronic medical record data to describe monkeypox infections after a single dose of Modified Vaccinia Ankara-Bavarian Nordic vaccine, a live, nonreplicating vaccine indicated for prevention of smallpox and monkeypox infection in adults.
This Viewpoint discusses a federal policy loophole that allows psychotropic cannabis products to be commercially marketed and sold across the US, even in states where recreational cannabis is not legal.
This Viewpoint discusses the ways in which the tobacco industry can advance their stated goals of harm reduction and a smoke-free future.
This Viewpoint outlines how the revival of now defunct state-level antisodomy laws would harm the health care of LGBTQ individuals should the US Supreme Court reverse itself and urges medical professionals and their societies to advocate for the immediate abolition of antisodomy laws.
In this narrative essay, a medical student discusses how observing a patient interacting with her adult daughter was a reminder of the ways in which the roles will eventually be reversed in her relationship with her own young daughter.
This article summarizes guidelines on identifying and addressing infertility in men from the American Urological Association and American Society for Reproductive Medicine.
A patient in his 40s presented to the emergency department with chest pain and diaphoresis, which had also occurred 2 days earlier. He had a 20 pack-year history of smoking but no family history of cardiovascular disease. The patient’s electrocardiogram showed biphasic T waves in leads V2 and V3. What would you do next?
This Medical News article discusses how cardiac xenotransplantation with genetically modified pig hearts might help relieve the shortage of human donor hearts.
This JAMA Patient Page describes the types of multiple sclerosis and its symptoms, diagnosis, treatment options, and recommended lifestyle modifications.