This noninferiority trial compares the effects of 2 antibiotic strategies, oral moxifloxacin vs intravenous ertapenem followed by oral levofloxacin, on hospital discharge without surgery and recurrent appendicitis over 1 year among adults presenting to the emergency department with uncomplicated acute appendicitis.
This randomized trial compares the effects on 24-month weight change of behavioral therapy delivered at US rural clinics via in-clinic individual visits or in-clinic group visits vs telephone group visits to patients with obesity.
This cohort study uses Framingham Heart Study (FHS) data to assess population-based incidence of transient ischemic attack (TIA), and the timing and long-term trends of stroke risk after TIA, among participants in the FHS Original, Offspring, and Third Generation cohorts from 1948 to 2017.
This internet survey study describes trends in respondents saying they were likely to accept vaccination for COVID-19 overall and by age, sex, race, and education between April and December 2020.
This study compares revenue of Maryland hospitals in March-July 2020 vs historical trends and assesses whether rate increases for inpatient and outpatient services that were permitted to offset pandemic-related decines in revenues were associated with changes to state hospital revenue.
This Viewpoint proposes policy options to forestall insolvency of the Medicare Hospital Insurance Trust Fund, including practical and politically palatable strategies to increase revenues and decrease spending to prevent looming shortfalls.
This Viewpoint reviews 3 policy options with broad political support that have been shown or are being studied to reduce gun violence: mapping sites for individuals to temporarily store their firearms during a crisis, voluntary do-not-sell lists, and extreme risk protection orders to restrict firearm purchase and possession by individuals at high risk of harm.
This Viewpoint explains how pharmaceutical companies use “nurse ambassadors,” paid registered nurses who interact with patients in home or phone visits to facilitate provision, administration, and refills of expensive medication, and implications of a 2020 settlement between AbbVie and the state of California requiring improved disclosures but largely allowing the programs to continue.
Following a September 2020 FDA announcement of a boxed warning for benzodiazepines, this Viewpoint reviews the relative benefits and risks of the drugs to reduce overuse in at-risk patients, moderate underuse in clinically appropriate instances, and guide judicious, rational prescribing.
In this narrative medicine essay a neonatal ICU nurse afraid to hold her newborn daughter after she dies draws comfort and a sense of connection years later from the memory of a parent she had unconsciously stigmatized, who held and loved her infant son at his death.
This narrative review summarizes the pathogenesis, diagnosis, and management of acute pancreatitis, including advances in risk stratification, fluid and nutritional management, and follow-up care and risk-reduction strategies.
This JAMA Insights review summarizes and interprets specialty society guidelines on the diagnosis and management of pancreatic cysts for primary care physicians, focusing on high-risk features, management, and surveillance
A 19-month-old boy fed a vegan diet after being diagnosed with milk, egg, and peanut allergies developed failure to thrive, speech delay, and acute irritability with widespread dermatitis and edema. What is the diagnosis and what would you do next?
This Medical News article discusses how Africa prevailed during the early onslaught of coronavirus disease 2019 and made plans to combat a second wave of the pandemic.
This Medical News Quick Uptake examines the debate about a link between vitamin D and COVID-19 risk.
This Arts and Medicine feature reviews Parasite, winner of the 2020 Academy Award for Best Picture, finding in its story of class struggle a way for clinicians and health systems to better understand structural origins of patients’ socioeconomic disadvantage and health inequity.
This JAMA Patient Page explains the causes, symptoms, and management of amblyopia, reduced vision in one or both eyes due to abnormal visual development during childhood.
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