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March 19, 2019, Vol 321, No. 11, Pages 1021-1128

In This Issue of JAMA

Highlights

Abstract Full Text
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JAMA. 2019;321(11):1021-1023. doi:10.1001/jama.2018.15245
Viewpoint

Rational Dispersion for the Introduction of Transcatheter Mitral Valve Repair Into Clinical Practice: Lessons Learned From TAVR

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JAMA. 2019;321(11):1043-1044. doi:10.1001/jama.2019.1542

This Viewpoint discusses the strategy of “rational dispersion” for new technology into clinical practice, and proposes patient and clinical selection criteria, follow-up and registry surveillance, and regionalization strategies that would guide rational staged rollout of transcatheter technology for mitral valve repair (TMVR).

Integrated Adherence Monitoring for Inhaler Medications

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JAMA. 2019;321(11):1045-1046. doi:10.1001/jama.2019.1289

This Viewpoint discusses integration of sensors to metered dose inhalers (MDIs) that provide measures of actuation and adherence and calls on physicians and manufacturers to make monitor-derived adherence measures a standard component of management of asthma, chronic obstructive pulmonary disease (COPD), and other MDI-treated lung disease.

Potential Implications of Private Equity Investments in Health Care Delivery

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JAMA. 2019;321(11):1047-1048. doi:10.1001/jama.2019.1077

This Viewpoint describes trends favoring private equity acquisition of health care practices and companies, and calls for research to better characterize potential risks and benefits relative to health care quality, outcomes, and costs.

Enhanced Recovery After Surgery in the United States: From Evidence-Based Practice to Uncertain Science?

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JAMA. 2019;321(11):1049-1050. doi:10.1001/jama.2019.1070

This Viewpoint characterizes the evidence base underlying existing interventions to reduce complications and improve patient outcomes after surgery, and emphasizes the need for science to guide extension and development of new interventions in the face of pressures to use length-of-stay (LOS) as the primary measure of enhanced recovery and to use interventions shown effective for one population and setting to others.

A Piece of My Mind

Bearing Witness and Finding Meaning

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JAMA. 2019;321(11):1051-1052. doi:10.1001/jama.2019.1292

In this narrative medicine essay, a palliative care physician’s experience—holding the hand of a man who was flung to a curb after miscalculating a light change as he dashed across the street causing him to be struck by truck—cured her of fainting at the sight of pain, which enabled her to choose a career in palliative care.

Editorial

The Evidence Supporting Cardiovascular Guidelines: Is There Evidence of Progress in the Last Decade?

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JAMA. 2019;321(11):1053-1054. doi:10.1001/jama.2019.2018

Reconsidering the Importance of the Association of Egg Consumption and Dietary Cholesterol With Cardiovascular Disease Risk

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JAMA. 2019;321(11):1055-1056. doi:10.1001/jama.2019.1850

Thank You to Peer Reviewers, Authors, and Readers of JAMA

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JAMA. 2019;321(11):1057-1058. doi:10.1001/jama.2019.1465
Original Investigation

Effect of Catheter Ablation vs Antiarrhythmic Medication on Quality of Life in Patients With Atrial Fibrillation: The CAPTAF Randomized Clinical Trial

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JAMA. 2019;321(11):1059-1068. doi:10.1001/jama.2019.0335

This randomized trial compares the effects of pulmonary vein isolation using radiofrequency ablation vs antiarrhythmic medication on self-reported quality of life at 1 year in patients with atrial fibrillation and previous medication failure.

Levels of Evidence Supporting American College of Cardiology/American Heart Association and European Society of Cardiology Guidelines, 2008-2018

Abstract Full Text
JAMA. 2019;321(11):1069-1080. doi:10.1001/jama.2019.1122

This systematic review of current and prior American College of Cardiology/American Heart Association and European Society of Cardiology guidelines summarizes the class and level of evidence (LOE) supporting guideline recommendations and changes in LOEs over time.

Associations of Dietary Cholesterol or Egg Consumption With Incident Cardiovascular Disease and Mortality

Abstract Full Text
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JAMA. 2019;321(11):1081-1095. doi:10.1001/jama.2019.1572

This pooled cohort study reports that consumption of an additional 300 mg of dietary cholesterol per day or an additional half egg per day is significantly associated with higher risk of incident cardiovascular disease (CVD) events and all-cause mortality.

JAMA Guide to Statistics and Methods

Choosing a Time Horizon in Cost and Cost-effectiveness Analyses

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JAMA. 2019;321(11):1096-1097. doi:10.1001/jama.2019.1153

This JAMA Guide to Statistics and Methods reviews considerations that go into investigators’ choice of time over which to define and measure the benefits and costs of interventions in risk-benefit and cost-effectiveness analyses.

JAMA Insights

Clinical Update

Evaluation of Cardiac Rhythm Abnormalities From Wearable Devices

Abstract Full Text
JAMA. 2019;321(11):1098-1099. doi:10.1001/jama.2019.1681

This Clinical Update reviews the technologies underlying dysrhythmia detection by Apple's smartwatch and other personal mobile devices, accuracy of the devices for detecting atrial fibrillation and clinically significant tachycardias and bradycardia, and it proposes an algorithm for how clinicians should respond to each.

JAMA Clinical Guidelines Synopsis

Management of Patients With Atrial Fibrillation

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JAMA. 2019;321(11):1100-1101. doi:10.1001/jama.2019.1264

This JAMA Clinical Guidelines Synopsis summarizes the AHA/ACC/HRS 2019 update of the societies’ guideline for managing patients with atrial fibrillation, focusing on use of novel oral anticoagulants (NOACs) and procedural interventions such as left atrial appendage closure (LAAC) and catheter ablation.

Research Letter

Disclosure of Religious Identity and Health Care Practices on Catholic Hospital Websites

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JAMA. 2019;321(11):1103-1104. doi:10.1001/jama.2019.0133

This study examines whether Catholic hospitals disclose their religious identity and health care practices based on the church’s teachings on their websites.

Medical News & Perspectives

Clinics Aim to Improve Post-ICU Recovery

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JAMA. 2019;321(11):1036-1038. doi:10.1001/jama.2019.0420

This Medical News story discusses initiatives aimed at improving recovery from life-threatening illnesses after release from the intensive care unit.

Older Adults May Fuel an Upturn in Eczema Cases

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JAMA. 2019;321(11):1038-1039. doi:10.1001/jama.2019.0384

This Medical News & Perspectives article describes a report showing that the prevalence of atopic eczema rebounds in older adults.

News From the Food and Drug Administration

New Treatment for Rare Blood Clotting Disorder

Abstract Full Text
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JAMA. 2019;321(11):1042. doi:10.1001/jama.2019.1826

Breast Implant–Associated Lymphoma

Abstract Full Text
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JAMA. 2019;321(11):1042. doi:10.1001/jama.2019.1936

Oversight of Supplements

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JAMA. 2019;321(11):1042. doi:10.1001/jama.2019.1937
The JAMA Forum

Shaking Things Up in California

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JAMA. 2019;321(11):1039-1040. doi:10.1001/jama.2019.1472
Global Health

Higher HIV Rates in Adolescent Girls Related to Drought in Lesotho

Abstract Full Text
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JAMA. 2019;321(11):1041. doi:10.1001/jama.2019.1377

Venezuela’s Infant Death Rate Rises Amid Worsening Humanitarian Crisis

Abstract Full Text
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JAMA. 2019;321(11):1041. doi:10.1001/jama.2019.1933

WHO’s Top Health Threats for 2019

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JAMA. 2019;321(11):1041. doi:10.1001/jama.2019.1934
Comment & Response

Challenges in Research on Suicide Prevention

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JAMA. 2019;321(11):1104-1105. doi:10.1001/jama.2018.21955

Challenges in Research on Suicide Prevention

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JAMA. 2019;321(11):1105. doi:10.1001/jama.2018.21951

Challenges in Research on Suicide Prevention—Reply

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JAMA. 2019;321(11):1105-1106. doi:10.1001/jama.2018.21963

Reducing the Burden of Fellowship Interviews

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JAMA. 2019;321(11):1106. doi:10.1001/jama.2018.21590

Reducing the Burden of Fellowship Interviews

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JAMA. 2019;321(11):1106-1107. doi:10.1001/jama.2018.21586

Reducing the Burden of Fellowship Interviews—Reply

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JAMA. 2019;321(11):1107. doi:10.1001/jama.2018.21596
Poetry and Medicine

The War of All Against All

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JAMA. 2019;321(11):1108. doi:10.1001/jama.2018.17815
JAMA Revisited

Andreas Vesalius and Harvey Cushing: Tradition and Inspiration

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JAMA. 2019;321(11):1109. doi:10.1001/jama.2018.15253
Peer Reviewers List

JAMA Peer Reviewers in 2018

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JAMA. 2019;321(11):1110-1122. doi:10.1001/jama.2019.0146
JAMA Patient Page

Cardiac Catheter Ablation for Heart Rhythm Abnormalities

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JAMA. 2019;321(11):1128. doi:10.1001/jama.2018.9832

This JAMA Patient Page describes why and how cardiac catheter ablation is used to correct atrial fibrillation and other heart rhythm abnormalities.

JAMA Masthead

JAMA

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JAMA. 2019;321(11):1025-1026. doi:10.1001/jama.2018.15246
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