This randomized clinical trial compares the efficacy of percutaneous transluminal angioplasty and stenting plus medical therapy vs medical therapy alone in reducing the risk of stroke or death among patients with symptomatic severe intracranial atherosclerotic stenosis.
This clinical trial examines whether intravenous tirofiban could improve disability severity without increasing symptomatic intracranial hemorrhage or mortality in patients with acute ischemic stroke and proximal large vessel occlusions undergoing endovascular treatment.
This systematic review and individual patient data meta-analysis of randomized clinical trials compares the effects of ticagrelor dual antiplatelet therapy or ticagrelor monotherapy with aspirin on saphenous vein graft failure among patients undergoing coronary artery bypass graft surgery.
This study assesses time trends in incidence of stroke, transient ischemic attack, and other major vascular events at younger vs older ages in a population living in Oxfordshire, England, in 2002-2018.
This study uses data from US Food and Drug Administration (FDA) databases to quantify approval of high-risk cardiovascular devices for use in pediatric populations and assess the clinical evidence supporting the approvals.
This study uses data obtained through an updated version of the Brazilian National Health System Questionnaire for COVID-19 to assess olfactory dysfunction in patients with mild COVID-19 in Rio de Janeiro, Brazil.
This Viewpoint discusses how the coronavirus pandemic has highlighted the burnout felt by the entire health care workforce, including nursing assistants, transport personnel, and clerical staff, and how this can be addressed through a blended approach that improves workforce well-being, the health care system, and patients’ health.
This Viewpoint discusses shortcomings of current electronic health record (EHR) implementation, summarizes how the CMS SAFER Guides can in part address these shortcomings by lessening cognitive load of EHR tasks, and proposes a 7-dimension SMARTER Guide to further lessen cognitive load, increase cognitive support, and advance measurement and improvement of EHR technology.
This Viewpoint discusses the need to expand early cancer detection to include both screening and symptom detection to achieve the goal of diagnostic excellence for cancer.
In this narrative medicine essay, an infectious diseases physician ponders how working through the COVID pandemic has changed her even though the words to explain it elude her and finds solace in the experience described in the Camus novel The Plague.
This JAMA Insights in Women’s Health series summarizes the prevalence of cardiovascular disease among women of childbearing age, the most effective forms of contraception based on the patient’s medical condition and preference, and the risks and adverse effects associated with contraindicated forms of contraception.
This article summarizes a guideline on the prevention and treatment of mild to moderate asthma, produced by the Global Initiative for Asthma (GINA).
This Medical News article is an interview with Alka Kanaya, MD, and Namratha Kandula, MD, MPH, principal investigators on the Mediators of Atherosclerosis in South Asians Living in America (MASALA) prospective cohort study.
Clinicians face an array of legal uncertainties surrounding abortion care since the US Supreme Court overturned Roe v Wade in June.
This Arts and Medicine essay reviews the work of visual artist Paula Siniatkina, who has used her experience as a patient previously quarantined and treated for tuberculosis to create art intended to represent and destigmatize the disease.
This JAMA Patient Page describes carpal tunnel syndrome and its symptoms, risk factors, diagnosis, and treatment options.