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December 1, 1962

Pain and Spasticity in Patients with Spinal Cord Dysfunction: Results of a Follow-Up Study

Author Affiliations

New York City
Associate Director (Dr. Kaplan), Director (Dr. Grynbaum), and Fellow (Dr. Lloyd), Department of Physical Medicine and Rehabilitation, Bellevue Hospital, and Professor and Chairman (Dr. Rusk), Department of Physical Medicine and Rehabilitation, New York University Medical College.

JAMA. 1962;182(9):918-925. doi:10.1001/jama.1962.03050480024006

This retrospective and continuing follow-up study analyzes the incidence and treatment of pain and spasticity in disease of the spinal cord. Of 44 patients with upper motor neuron involvement, 31 had initial spasticity which persisted in 28 to the present and developed in 5 others during the interim. Pain, usually mild, was found in 19 initially; it was still present in 16 at follow-up examination and developed during the interim in 13 others. Spasticity tended to occur in the lower extremities, flexors, and extensors, and prevented daily activities. Drugs were mildly effective. Pain tended to persist but did not prevent daily function. It was commonly found in the lower extremities, at the level of the lesion, in the region of the lower abdomen, and elsewhere. It was often neglected therapeutically.

Newman, L. B.; Arieff, A. J.; and Wasserman, R. R.:  Present Status in Management of Spasticity and Spasm: Preliminary Report ,  Arch Phys Med , 1954, pp. 427-436.
Veterans' Administration Technical Bulletin, TB10-503, Spinal Cord Injuries, 1948, pp. 8-13.
Levine, M. G., et al.:  Relaxation of Spasticity by Physiological Technics ,  Arch Phys Med , 1954, pp. 214-223.
D'Oronzio, G. B.; Lindenaur, H. J.; and Ebel, A.:  Evaluation of "Sinaxar" on Spasticity ,  Proceedings of Seventh Annual Clinical Paraplegia Conference, 1958 , pp. 141-151.
Weiss, A. A.; D'Oronzio, G. B.; and Ebel, A.:  Evaluation of Effect of Zoxazolamine (Flexin) on Spasticity ,  Proceedings of Fifth Annual Clinical Paraplegia Conference, 1956 , pp. 53-64.
Koppel, A.:  Pain Index-Method for Determining Progress of Treatment ,  Arch Phys Med , 1956, pp. 500-505.
Lehmann, J. F.; Baunner, G. D.; and Stow, R. W.:  Pain Threshold Measurements after Therapeutic Application of Ultrasound, Microwaves, and Infrared ,  Arch Phys Med , 1958, pp. 560-565
Zankel, H. T., and Sutton, B. B.:  Paraplegic Program under Physical Medicine and Rehabilitation: One Year's Experience ,  Arch Phys Med , 1954, pp. 296-302.
Hastings, J. E. F.:  Study of Paraplegic Patient , Workmen's Compensation Board, Ontario, 1954.
Stillwell, G. K.:  Battery Stimulation for Denervated Muscles ,  Arch Phys Med , 1954, pp. 689-692.
Kurnick, N. B.:  Drug Therapy of Autonomic Hyperreflexia in Patients with Spinal Cord Lesions ,  Proceedings of Third Annual Clinical Paraplegia Conference, 1954 , pp. 43-44.
Gucher, T., III:  Rehabilitation in Injuries of Spinal Cord ,  J Occup Med , 1952, pp. 61-64.
Hoefnagel, D.; Van Den Noort, S.; and Denny-Brown, D.:  Muscle Spasm and Abnormal Postures Resulting from Damage to Interneurones in Spinal Cord ,  Arch Neurol , 1960, pp. 500-512.
Akeson, W. H.:  Experimental Study of Joint Stiffness ,  J Bone Joint Surg , 1961, pp. 1022-1034.
Grynbaum, B. B., et al.: Methodology and Initial Findings in Follow-up Study of Spinal Cord Dysfunction, unpubished data.
Psaki, R. C., and Treanor, W. J.:  Afferent Influences in Management of Spastic Paresis ,  Arch Phys Med 1956, pp. 214-217.
Herman, R.:  On Physiologic Basis of Tone, Spasticity and Rigidity ,  Arch Phys Med 1962, pp. 1-12.