[Skip to Content]
Sign In
Individual Sign In
Create an Account
Institutional Sign In
OpenAthens Shibboleth
Purchase Options:
[Skip to Content Landing]
Article
December 8, 1962

A New Angiographic Contrast Medium, Sodium Iothalamate 80%: A Clinical and Experimental Evaluation

Author Affiliations

Nashville, Tenn.
From the S. R. Light Laboratory for Surgical Research and the Department of Surgery, the Vanderbilt University Medical Center, and the Thayer Veterans Administration Hospital.; Dr. Foster is a member of the American College of Surgeons, and a J. S. Kemper Foundation Research Scholar.

JAMA. 1962;182(10):1009-1013. doi:10.1001/jama.1962.03050490033007
Abstract

A new angiographic contrast medium, sodium iothalamate 80%, has been tested in experimental animals by standardized toxicity tests. The results were compared to results obtained with other currently employed concentrated media. Sodium iothalamate proved least toxic of any medium tested. This new medium has high radiodensity and low viscosity. In 248 clinical angiograms sodium iothalamate proved superior for all uses involving intravascular injection of concentrated contrast media.

References
1.
Abrams, H. L.:  Radiologic Aspects of Operable Heart Disease: III. Hazards of Retrograde Thoracic Aortographic: Survey ,  Radiology 68:812, 1957.
2.
Killen, D. A., and Foster, J. H.:  Spinal Cord Injury as Complication of Aortography ,  Ann Surg 152:211, 1960.Crossref
3.
McAfee, J. G.:  Survey of Complications of Abdominal Aortography ,  Radiology 68:825, 1957.
4.
Foster, J. H.; Sessions, R. T.; and Killen, D. A.:  Studies in Prevention of Toxic Reactions Incident to Contrast Angiography ,  Bull Soc Int Chir , in press.
5.
Killen, D. A.; Lance, E. M.; and Owens, G.:  Relative Suitability of Urokon 70 Per Cent and Hypaque 90 Per Cent for Use as Aortographic Contrast Media ,  Surgery 45:436, 1959.
6.
Killen, D. A., and Lance, E. M.:  Experimental Appraisal of Agents Employed as Angiographic and Aortographic Contrast Media: II. Nephrotoxicity ,  Surgery 47:260-265 ( (Feb.) ) 1960.
7.
Lance, E. M., and Killen, D. A.:  Experimental Appraisal of Agents Employed as Angiographic and Aortographic Contrast Media: I. Neurotoxicity ,  Surgery 46:1109, 1959.
8.
Lance, E. M., and Killen, D. A.:  Experimental Appraisal of Agents Employed as Angiographic and Aortographic Media: III. Cardiovascular Response to Intra-Aortic Dissemination ,  Amer J Surg 101:343, 1961.Crossref
9.
Sessions, R. T.; Killen, D. A.; and Foster, J. H.:  Low Molecular Weight Dextran as Protective Agent Against Toxic Effect of Urokon ,  Amer Surg , in press.
10.
Foster, J. H., and Killen, D. A.:  Experimental Appraisal of New Angiographic contrast Medium ,  Surg Gynec Obstet 113:234, 1961.
11.
Crawford, E. S., et al.:  Complications of Aortography ,  Surg Gynec Obstet 104:129, 1957.
12.
Foster, J. H., and Killen, D. A.:  Aortography and Peripheral Arteriography: Analyses of Results in University Center ,  Ann Surg 149:321, 1959.Crossref
13.
Lehman, J. S., and Debbas, J. N.:  Evaluation of Cardiovascular Contrast Media ,  Radiology 76:548, 1961.
14.
Margolis G., et al.:  Contrast Medium Injury to Spinal Cord ,  J Neurosurg 16:390, 1959.Crossref
×