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December 8, 1962

A New Angiographic Contrast Medium, Sodium Iothalamate 80%: A Clinical and Experimental Evaluation

Author Affiliations

Nashville, Tenn.
From the S. R. Light Laboratory for Surgical Research and the Department of Surgery, the Vanderbilt University Medical Center, and the Thayer Veterans Administration Hospital.; Dr. Foster is a member of the American College of Surgeons, and a J. S. Kemper Foundation Research Scholar.

JAMA. 1962;182(10):1009-1013. doi:10.1001/jama.1962.03050490033007

A new angiographic contrast medium, sodium iothalamate 80%, has been tested in experimental animals by standardized toxicity tests. The results were compared to results obtained with other currently employed concentrated media. Sodium iothalamate proved least toxic of any medium tested. This new medium has high radiodensity and low viscosity. In 248 clinical angiograms sodium iothalamate proved superior for all uses involving intravascular injection of concentrated contrast media.

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