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In a randomized clinical trial that enrolled 95 children and adults with type 1 diabetes mellitus
and impaired hypoglycemic awareness, Ly and colleagues investigated the effect of sensor-augmented
insulin pump therapy with an automated insulin suspension function on the incidence of major
hypoglycemic events. The authors report that compared with standard insulin pump therapy,
sensor-augmented insulin pump therapy with automated insulin suspension—for up to 2 hours when
patients did not respond to a low glucose alarm—reduced the rate of severe and moderate
hypoglycemic events. In an Editorial, Choudhary discusses the potential of sensor-augmented insulin
pump therapy with a threshold-suspension function to reduce episodes of nocturnal hypoglycemia.
Highlights. JAMA. 2013;310(12):1203–1205. doi:10.1001/jama.2013.5325
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