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Many patients with resistant hypertension have obstructive sleep apnea (OSA). To assess the effect of continuous positive airway pressure (CPAP) treatment on blood pressure in these patients, Martín-García and colleagues randomly assigned 194 patients with resistant hypertension and OSA to receive 12 weeks of CPAP or no CPAP therapy with no changes made in blood pressure medications. The authors report that patients receiving CPAP treatment experienced a decrease in 24-hour mean and diastolic blood pressure and an improvement in the nocturnal blood pressure pattern.
Little is known about long-term weight loss and health outcomes after bariatric surgery. In a 3-year follow-up of 2458 adults who underwent Roux-en-Y gastric bypass (RYGB) or laparoscopic adjustable gastric banding (LAGB) for severe obesity, Courcoulas and colleagues found that median weight loss was 41 kg for RYGB and 20 kg for LAGB participants, with the majority experiencing maximum weight change during the first year. Improvements in comorbid hyperglycemia, hyperlipidemia, and hypertension were variable but of greater magnitude with RYGB than LAGB. In an Editorial, Ikramuddin and Livingston discuss outcomes of bariatric surgery.
Highlights. JAMA. 2013;310(22):2363–2365. doi:10.1001/jama.2013.5455
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