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Recent welcome news from the Joint United Nations Programme on HIV/AIDS reported a 33% reduction in new human immunodeficiency virus (HIV) infections in adults and children globally in 2012 compared with the number of incident infections in 2001.1 The evidence of progress in preventing expansion of HIV is an impressive tribute to the efforts of many clinicians and researchers, but it is silhouetted against a backdrop of an estimated 35.3 million persons worldwide having HIV infection.1
In the United States, the number of cases of new HIV infections, estimated at approximately 50 000 each year,2,3 remains concerning, and despite evidence in support of preexposure chemoprophylaxis for HIV prevention, implementation issues may impede these interventions in fulfilling their promise.4 In terms of treatment, much progress has occurred with the development of effective therapies,5 but questions of resistance and tolerability remain.
Smith JM, Fontanarosa PB. HIV/AIDS—Building on Progress, Acquiring New Knowledge: Call for Papers for the 2014 JAMA Theme Issue. JAMA. 2013;310(24):2621. doi:10.1001/jama.2013.284516
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