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Screening ultrasound may reveal small breast cancers not seen on mammography. Berg and colleagues Article report results of a clinical trial in which women at increased risk for breast cancer and presenting for routine mammography were randomly assigned to undergo either mammography plus ultrasound or mammography alone. Standardized scanning and interpretative criteria were used to compare the diagnostic yield of the 2 screening approaches. The authors found that the addition of a single screening ultrasound examination to mammography would detect an additional 1.1 to 7.2 cancers per 1000 high-risk women. In an editorial, Kuhl Article discusses the strengths and limitations of mammography, ultrasonography, and magnetic resonance imaging for breast cancer screening.
This Week in JAMA . JAMA. 2008;299(18):2121. doi:10.1001/jama.299.18.2121
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