Customize your JAMA Network experience by selecting one or more topics from the list below.
Patients with suspected deep vein thrombosis (DVT) of the lower extremities may be evaluated with either proximal vein 2-point ultrasonography or whole-leg ultrasonography. To assess whether the 2 strategies are equivalent, Bernardi and colleagues Article randomly assigned 2098 consecutive outpatients with symptoms of a first-episode lower-extremity DVT to undergo either 2-point ultrasonography (plus D-dimer testing) or whole-leg color-coded Doppler ultrasonography. Patients with normal findings were followed up for 3 months. The authors report the 2 diagnostic strategies were equivalent for the detection of symptomatic venous thromboembolism. In an editorial, Landefeld Article discusses the diagnosis of DVT.
Pharmacological treatment of benign prostatic hyperplasia includes 5-α reductase inhibitors (eg, finasteride), which block the conversion of testosterone to dihydrotestosterone. Whether 5-α reductase inhibitors adversely affect bone health is not clear. In a case-control study involving patients with a diagnosis of benign prostatic hyperplasia, Jacobsen and colleagues assessed the association between use of 5-α reductase inhibitors and incident hip fracture. The authors found no association of exposure to 5-α reductase inhibitors with increased risk of hip fracture.
This Week in JAMA . JAMA. 2008;300(14):1621. doi:10.1001/jama.300.14.1621
Create a personal account or sign in to: