[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Citations 0
This Week in JAMA
October 8, 2008

This Week in JAMA

JAMA. 2008;300(14):1621. doi:10.1001/jama.300.14.1621

Patients with suspected deep vein thrombosis (DVT) of the lower extremities may be evaluated with either proximal vein 2-point ultrasonography or whole-leg ultrasonography. To assess whether the 2 strategies are equivalent, Bernardi and colleagues Article randomly assigned 2098 consecutive outpatients with symptoms of a first-episode lower-extremity DVT to undergo either 2-point ultrasonography (plus D-dimer testing) or whole-leg color-coded Doppler ultrasonography. Patients with normal findings were followed up for 3 months. The authors report the 2 diagnostic strategies were equivalent for the detection of symptomatic venous thromboembolism. In an editorial, Landefeld Article discusses the diagnosis of DVT.

Pharmacological treatment of benign prostatic hyperplasia includes 5-α reductase inhibitors (eg, finasteride), which block the conversion of testosterone to dihydrotestosterone. Whether 5-α reductase inhibitors adversely affect bone health is not clear. In a case-control study involving patients with a diagnosis of benign prostatic hyperplasia, Jacobsen and colleagues assessed the association between use of 5-α reductase inhibitors and incident hip fracture. The authors found no association of exposure to 5-α reductase inhibitors with increased risk of hip fracture.