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Author Affiliations: Knowledge and Encounter Research Unit, Department of Medicine and Department of Health Sciences Research, College of Medicine, Mayo Clinic, Rochester, Minnesota (Dr Montori); and Clinical Advances Through Research and Information Translation (CLARITY) Research Group, Department of Clinical Epidemiology and Biostatistics, and Department of Medicine, Faculty of Health Sciences, McMaster University, Hamilton, Ontario, Canada (Dr Guyatt).
A new paradigm for medical practice is emerging. Evidence-based medicine de-emphasizes intuition, unsystematic clinical experience, and pathophysiologic rationale as sufficient grounds for clinical decision making and stresses the examination of evidence from clinical research. Evidence- based medicine requires new skills of the physician, including efficient literature searching and the application of formal rules of evidence evaluating the clinical literature.
See PDF for full text of the original JAMA article.
Montori VM, Guyatt GH. Progress in Evidence-Based Medicine. JAMA. 2008;300(15):1814–1816. doi:10.1001/jama.300.15.1814
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