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This Week in JAMA
December 24 2008

This Week in JAMA

JAMA. 2008;300(24):2829. doi:10.1001/jama.2008.891

There is some evidence that sleep duration is related to several risk factors for coronary artery calcification. In an analysis of data from the Coronary Artery Risk Development in Young Adults study, King and colleagues assessed whether objective and subjective measures of sleep duration and quality were associated with the incidence of calcification at a 5-year follow-up examination. The authors found that objectively measured longer sleep duration was associated with a decreased incidence of calcification, which was independent of other potential mediators and confounders.


Qato and colleagues analyzed data from a nationally representative sample of community-residing adults aged 57 through 85 years to estimate the prevalence and patterns of medication use, including concurrent use and potential major drug-drug interactions. The authors report that 81% (95% confidence interval [CI], 79.4%-83.5%) of surveyed individuals used at least 1 prescription medication, 42% (95% CI, 39.7%-44.8%) used at least 1 over-the-counter medication, and 49% (95% CI, 46.2%-52.7%) used a dietary supplement. Concurrent use of medications and supplements was common, and 4% of the survey respondents were potentially at risk of a major drug-drug interaction.