Updated Recommendations of the Advisory Committee on Immunization Practices (ACIP) Regarding Routine Poliovirus Vaccination | Vaccination | JAMA | JAMA Network
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News From the Centers for Disease Control and Prevention
November 25, 2009

Updated Recommendations of the Advisory Committee on Immunization Practices (ACIP) Regarding Routine Poliovirus Vaccination

JAMA. 2009;302(20):2199. doi:

MMWR. 2009;58:829-830

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This report updates Advisory Committee on Immunization Practices (ACIP) recommendations for routine poliovirus vaccination. These updates aim to (1) emphasize the importance of the booster dose at age ≥4 years, (2) extend the minimum interval from dose 3 to dose 4 from 4 weeks to 6 months, (3) add a precaution for the use of minimum intervals in the first 6 months of life, and (4) clarify the poliovirus vaccination schedule when specific combination vaccines are used.

On June 17, 1999, ACIP recommended that all poliovirus vaccine administered in the United States be an inactivated poliovirus vaccine (IPV) beginning January 1, 2000. This policy was implemented to eliminate the risk for vaccine-associated paralytic poliomyelitis, a rare condition that has been associated with use of the live oral poliovirus vaccine (OPV). Since 1999, no OPV has been distributed in the United States. Under these ACIP recommendations, the routine IPV vaccination schedule in the United States consists of 4 doses administered at ages 2 months, 4 months, 6-18 months, and 4-6 years with the minimum interval between all IPV doses as 4 weeks.1,2

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