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Boskey AL. Musculoskeletal Disorders and Orthopedic Conditions. JAMA. 2001;285(5):619–623. doi:10.1001/jama.285.5.619
Author Affiliation: Hospital for Special Surgery, and Weill (Cornell University) Medical College and Graduate School of Medical Sciences, New York, NY.
Ongoing advances in orthopedics include discoveries of functions of
matrix proteins, development of new implant materials that are more durable
and more compatible with magnetic resonance imaging, and identification of
genes causing musculoskeletal disorders and disease. The Human Genome Project
will further clarify the genetic basis of specific musculoskeletal disorders,
enhancing risk factor identification, diagnosis, and therapy. Engineered,
cell-based materials will replace metals and plastics in implants, and new
composite materials will promote bone in-growth.
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