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This Week in JAMA
August 28, 2002

This Week in JAMA

JAMA. 2002;288(8):923. doi:10.1001/jama.288.8.923

The relationship between environmental exposures early in life and subsequent development of allergic disease is not well understood. In this prospective birth cohort study, Ownby and colleaguesArticle found that risk of allergic sensitization to common aeroallergens at age 6 to 7 years was lower among children exposed to 2 or more dogs or cats in the first year of life than among children exposed to 1 dog or cat or those without any early dog or cat exposure. In an editorial, Platts-MillsArticle discusses immunologic mechanisms that may explain the different associations that have been observed between allergen exposure and risk of allergic sensitization and disease.