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Annual influenza revaccination of institutionalized elderly individuals
is associated with improved survival, but whether a mortality benefit exists
for persons living in the community is not clear. Voordouw and colleagues
investigated the effect of annual influenza revaccination vs no vaccination
on mortality in community-dwelling elderly individuals aged 65 years and older.
They found that annual influenza revaccination was associated with a significant
mortality reduction among those aged 70 years and older and those with and
without chronic comorbidities.
Professional guidelines recommend early invasive management (cardiac
catheterization within 48 hours of presentation) for high-risk patients with
non–ST-segment elevation acute coronary syndromes (NSTE ACS). However,
it is not known whether this recommendation is reflected in clinical practice.
Bhatt and colleagues conducted a multicenter observational study evaluating
the care and outcomes for patients at high-risk of NSTE ACS and report use
and predictors of early invasive management and in-hospital mortality. They
found fewer than half the patients had early catheterization. Patients who
did had few significant comorbidities, were likely to be cared for by cardiologists,
and had lower in-hospital mortality.
This Week in JAMA . JAMA. 2004;292(17):2049. doi:https://doi.org/10.1001/jama.292.17.2049
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