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Despite near universal exposure to gluten-containing wheat products,
only a small percentage of susceptible individuals develop celiac disease,
suggesting other factors are involved. Norris and colleaguesArticle collected dietary information for children at increased risk of celiac disease
to determine whether the timing of dietary gluten introduction is related
to development of celiac disease autoimmunity (CDA). They found that children
with gluten exposure in the first 3 months of life or after 6 months had a
significantly increased risk of CDA compared with children exposed to gluten
at 4 to 6 months of age. In an editorial, FarrellArticle discusses
the complexities of infant dietary practices and celiac disease risk.
This Week in JAMA . JAMA. 2005;293(19):2315. doi:10.1001/jama.293.19.2315
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