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This Week in JAMA
May 18, 2005

This Week in JAMA

JAMA. 2005;293(19):2315. doi:10.1001/jama.293.19.2315

Despite near universal exposure to gluten-containing wheat products, only a small percentage of susceptible individuals develop celiac disease, suggesting other factors are involved. Norris and colleaguesArticle collected dietary information for children at increased risk of celiac disease to determine whether the timing of dietary gluten introduction is related to development of celiac disease autoimmunity (CDA). They found that children with gluten exposure in the first 3 months of life or after 6 months had a significantly increased risk of CDA compared with children exposed to gluten at 4 to 6 months of age. In an editorial, FarrellArticle discusses the complexities of infant dietary practices and celiac disease risk.