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JAMA Patient Page
May 26, 2015

Deep Vein Thrombosis

JAMA. 2015;313(20):2090. doi:10.1001/jama.2015.4761

Deep vein thrombosis (DVT) is the formation of a blood clot in a vein deep under the skin.

The most common sites of deep vein clots are the lower leg and thigh. They can also occur in the pelvis and arm.

Causes of a thrombus (blood clot) include slow blood flow, an injury to the lining of a vein, or having blood with an increased tendency to clot.

The most common symptoms of DVT occur at the site of the clot. They include swelling, warmth, pain or tenderness, and redness of the skin. Deep vein thrombosis can also occur with no symptoms.