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Article
December 31, 1927

THE RECTAL ADMINISTRATION OF ETHER AND OIL: AND MORPHINE, MAGNESIUM SULPHATE AND ETHER IN SURGERY AND OBSTETRICS

Author Affiliations

Professor of Pharmacology, Cornell University Medical College, Member of Council on Pharmacy and Chemistry NEW YORK

JAMA. 1927;89(27):2258-2263. doi:10.1001/jama.1927.92690270024008
Abstract

III. Analgesia in Childbirth  Gwathmey, Donovan, O'Reagan, and Cowan,43 in 1923, published the first of a series of papers entitled "Painless Childbirth by Synergistic Methods." They state that, after more than fifteen different formulas had been used, the procedure was changed entirely. Formula 16 directs the hypodermic injection of morphine in 2 cc. of a 25 per cent solution of chemically pure magnesium sulphate. This dose of magnesium sulphate without the morphine is repeated once or twice, and this is followed by the rectal injection of a mixture composed of:They state that reliance is placed on the synergism of ether and magnesium sulphate the pains are four or five minutes apart and each lasting thirty seconds or more. The results varied but the majority of patients were helped and a few had comparatively painless labor.Gwathmey, McKenzie and Hudson,44 in 1924

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