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September 20, 2016

Errors in the Text and Supplement

JAMA. 2016;316(11):879. doi:10.1001/jama.2016.11097

In the Original Investigation entitled “Effect of Early vs Delayed Initiation of Renal Replacement Therapy on Mortality in Critically Ill Patients With Acute Kidney Injury: the ELAIN Randomized Clinical Trial” published in the May 24/31, 2016, issue of JAMA,1 there were a few errors in the text. During a revision, an adjusted analysis was removed but the description remained in the Methods; therefore, 2 sentences were removed: “A multivariable statistical analysis of the primary outcome was performed using Cox regression. After including all documented baseline characteristics of the patients in the model, backward elimination of variables was applied and a final model was established that included significant factors associated with the primary outcome.” Three changes were made to correct a number: (1) in the Results, a sentence was changed to "… 18 patients in the delayed group (15.1%), 17 of whom received RRT before reaching KDIGO stage 3 criteria"; (2) in the legend of Figure 2, a sentence was changed to “In the delayed group, 18 patients had an absolute indication for RRT”; (3) and in eTable 2 of Supplement 2, the column head was changed to “Absolute indication (n=17).” This article was corrected online.

Zarbock  A, Kellum  JA, Schmidt  C,  et al.  Effect of early vs delayed initiation of renal replacement therapy on mortality in critically ill patients with acute kidney injury: the ELAIN randomized clinical trial.  JAMA. 2016;315(20):2190-2199. PubMedGoogle ScholarCrossref