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Correction
February 7, 2017

Errors in Text, Figure, and Online Supplement

Author Affiliations
 

Copyright 2016 American Medical Association. All Rights Reserved.

JAMA. 2017;317(5):538. doi:10.1001/jama.2016.18601

In the Preliminary Communication entitled “Diagnostic Test Accuracy of a 2-Transcript Host RNA Signature for Discriminating Bacterial vs Viral Infection in Febrile Children,” published in the August 23, 2016, issue of JAMA,1 there were errors in the text, a figure, and the online Supplement. In the abstract Results and in the Key Points Findings, the sensitivity value reported as 100% (95% CI, 100%-100%) should have been reported as 100% (95% CI, 85%-100%). In the text Results, “Identification of Minimal Transcript Signatures” section, the first sensitivity value reported as 100% (95% CI, 100%-100%) should have been reported as 100% (95% CI, 69%-100%), and the second sensitivity value reported as 100% (95% CI, 100%-100%) should have been reported as 100% (95% CI, 85%-100%); in the “Implementation of a DRS” section, the sensitivity value reported as 100% (95% CI, 100%-100%) should have been reported as 100% (95% CI, 85%-100%). In Figure 1, in the “Discovery groups (IRIS study)” flow, in the “249 Selected” box, the value reported for “Definite viral infection (all)” should have been 92 rather than 73, and the value reported for “Subset of probable bacterial infection…” should have been 105, rather than 124. In the “Validation groups” flow, the “48 Samples underwent HT-12 v4 microarray gene expression analysis” box should also have reported “45 Samples underwent Ref-8 microarray gene expression analysis.” In the online Supplement, the Supplementary Statistical Methods, eTable 4, and eTable 6 contained errors that have been corrected. This article was corrected online.

References
1.
Herberg  JA, Kaforou  M, Wright  VJ,  et al; IRIS Consortium.  Diagnostic test accuracy of a 2-transcript host RNA signature for discriminating bacterial vs viral infection in febrile children.  JAMA. 2016;316(8):835-845.PubMedGoogle ScholarCrossref
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