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In This Issue of JAMA
November 20, 2018


JAMA. 2018;320(19):1955-1957. doi:10.1001/jama.2017.12636

Intensive care unit nurses are exposed to occupational stress in the form of time pressure, high workloads, interpersonal conflicts, and moral and spiritual distress. El Khamali and colleagues for the SISTRESSREA Study Group enrolled 198 intensive care unit nurses in a randomized clinical trial and found that a multimodal intervention with education, role-play, and debriefing resulted in a lower prevalence of job strain. In an Editorial, Seaman and colleagues suggest that reducing job-related stress can increase the productivity of nurses and improve their quality of care.


Audio Interview, CME, and Visual Abstract

Preliminary studies have suggested that treatment with alkaline phosphatase can improve kidney function in patients with sepsis. Pickkers and colleagues for the STOP-AKI Investigators randomized 301 patients with sepsis-associated acute kidney injury (AKI) and found that human recombinant alkaline phosphatase, compared with placebo, did not significantly improve short-term kidney function.