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JAMA Patient Page
April 9, 2019

Eosinophilic Esophagitis

Author Affiliations
  • 1Texas Tech University Health Sciences Center, Lubbock
JAMA. 2019;321(14):1418. doi:10.1001/jama.2019.1992

Eosinophilic esophagitis is an allergic condition that results in inflammation of the esophagus.

The defining characteristic of this disease is the abnormal presence of eosinophils, a type of white blood cell, in the esophagus. This condition has been linked to other allergic conditions, such as asthma, eczema, and food allergies. Eosinophilic esophagitis is caused by a combination of environmental factors, such as exposure to particular foods or allergens spread through the air, and genetic influences. Both children and adults can have eosinophilic esophagitis; it is more common in male individuals. Eosinophilic esophagitis is generally not life threatening; however, patients can experience food getting stuck in the esophagus.