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    1 Comment for this article
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    Post-Covid-19 Sequelae and Follow up
    Khichar Shubhakaran, MD(Med), D.M.(Neurology) | Senior Professor and head of Department of Neurology, MDM Hospital, Dr. S.N. Medical College, Jodhpur, India-342003
    A very important article about persistent symptoms after recovery from Covid-19. Of course all these symptoms may have some component of psychology but the persistent symptoms are definitely organic and may have a long term impact on overall health care all over the globe.

    All these symptoms require close follow up, as pulmonary fibrosis in Covid-19 survivors have been reported from Mumbai in India (1), and from Wuhan in China also.

    While awaiting a vaccine for prevention, the understanding of the various sequelae of Covid-19 will help in studying the effects of interventions, like steroids and other immune
    modulators for pulmonary fibrosis (2), on long-term symptoms.

    References

    1. http://www.thehindubusinessline.com
    2. Spagnolo P, Balestro E, Aliberti S et al. Pulmonary fibrosis secondary to COVID-19:a call to arms ?Lancet Respir Med. 2020 Aug; 8(8): 750-752.
    CONFLICT OF INTEREST: None Reported
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    Citations 0
    Research Letter
    July 9, 2020

    Persistent Symptoms in Patients After Acute COVID-19

    Angelo Carfì, MD1; Roberto Bernabei, MD1; Francesco Landi, MD, PhD1; et al for the Gemelli Against COVID-19 Post-Acute Care Study Group
    Author Affiliations
    • 1Geriatrics Department, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy
    JAMA. 2020;324(6):603-605. doi:10.1001/jama.2020.12603

    In Italy, a large proportion of patients with coronavirus disease 2019 (COVID-19) presented with symptoms (71.4% of 31 845 confirmed cases as of June 3, 2020).1 Common symptoms include cough, fever, dyspnea, musculoskeletal symptoms (myalgia, joint pain, fatigue), gastrointestinal symptoms, and anosmia/dysgeusia.2-4 However, information is lacking on symptoms that persist after recovery. We assessed persistent symptoms in patients who were discharged from the hospital after recovery from COVID-19.

    In the waning phase of the pandemic, beginning on April 21, 2020, the Fondazione Policlinico Universitario Agostino Gemelli IRCCS in Rome, Italy, established a postacute outpatient service for individuals discharged from the hospital after recovery from COVID-19. All patients who met World Health Organization criteria for discontinuation of quarantine (no fever for 3 consecutive days, improvement in other symptoms, and 2 negative test results for severe acute respiratory syndrome coronavirus 2 [SARS-CoV-2] 24 hours apart) were followed up. At enrollment in the study, real-time reverse transcriptase–polymerase chain reaction for SARS-CoV-2 was performed and patients with a negative test result were included.

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