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Relationship Between the Hypophysis and the Thyroid
Professor Houssay and Drs. Magdalena, Biasotti and Mazzocco recently carried out experiments on the dog to find out the relationship of the hypophysis and the thyroid. They presented before the Sociedad Argentina de Biología of Buenos Aires a series of lectures on the results of their experiments. The removal of the thyroid produces hypertrophy of the hypophysis. The injection of the extract of the anterior lobe of the hypophysis causes hypertrophy and hyperfunction of the thyroid. The removal of the hypophysis is followed by the appearance of a typical change in the thyroid. The weight of the thyroid varied in the different groups of dogs used (dogs deprived entirely of the hypophysis and, as control, dogs in which a lesion of the tuber cinereum had been produced and dogs which were deprived either of the anterior or of the posterior lobes of the
BUENOS AIRES. JAMA. 1932;98(7):567–568. doi:10.1001/jama.1932.02730330049022
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