Study Aims to Identify Drugs That Could Be Repurposed for COVID-19 | Infectious Diseases | JAMA | JAMA Network
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Health Agencies Update
November 24, 2020

Study Aims to Identify Drugs That Could Be Repurposed for COVID-19

JAMA. 2020;324(20):2019. doi:10.1001/jama.2020.21726

The National Institute of Allergy and Infectious Diseases (NIAID) recently launched a study to determine whether drugs that are already approved or in the late stage of clinical development might merit testing in larger clinical trials as a coronavirus disease 2019 (COVID-19) treatment.

The ACTIV-5 Big Effect Trial is a collaboration with the Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV) program, a public-private partnership with the National Institutes of Health. The phase 2 randomized, double-blind clinical trial will compare different therapies to a common control group to see which drugs, if any, have relatively large treatment effects.

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