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October 1, 1932


JAMA. 1932;99(14):1190. doi:10.1001/jama.1932.02740660068030

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To the Editor:  —Referring to a communication on this subject in The Journal, September 3, page 849, the proper strength of nupercaine for subcutaneous injection is 0.1 per cent. The patient apparently suffered from an overdosage rather than an unusual susceptibility; "her reaction" was not what one might expect from an idiosyncrasy to one of the cocaine group; may I refer Dr. Jensen to an article which I contributed to The Journal (Local Anesthesia Agents: Preventive and Emergency Treatment of Toxicity with Especial Reference to Barbituric Acid Derivatives, Aug. 25, 1928, p. 555) and to a more recent discussion in the Journal of the Michigan State Medical Society, November, 1930 (Local Anesthetic Idiosyncrasies: Treatment).Dr. Jensen speaks of the usual preparation: such preparation should always include the administration of a soluble barbital preparation, and there are a number of them.In a discussion before a section at the annual session