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The author, now a professor of physiology, states in the preface that at one time he took an active part in the teaching of clinical medicine. He intends here to bridge the gap between clinical work and the sciences, in which attempt he essays to cover almost the whole field of physiology and the diseases of internal medicine. The subject matter pertaining to the physiology of the nervous system, respiration and circulation is presented in fairly good detail; that on the blood, the pathologic variations, the gastro-intestinal tract and in particular the liver and bile formation, the thyroid gland, metabolism and allergy are too incomplete to be of much value. Many statements are questionable or incorrect. Such, for example, are the theory of Lewis that fatigue is the result of accumulating toxins in the muscles with swelling and compression of the nerves as the accepted cause of pain; that of
The Science of Signs and Symptoms in Relation to Modern Diagnosis and Treatment: A Textbook for General Practitioners of Medicine. JAMA. 1932;99(25):2137. doi:10.1001/jama.1932.02740770067032
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