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January 3, 1948

Le diabète et sa pathogénie

JAMA. 1948;136(1):69. doi:10.1001/jama.1948.02890180071028

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Professor Ambard's monograph illustrates the famine of current scientific literature in war-torn countries.

It would be desirable if this eminent author could write a second edition based on the new work in diabetes. He could appreciate and thoroughly evaluate (1) the contributions of Cori; (2) the part played by hexokinase; (3) experimental production of diabetes by the creation of hyperglycemia announced by Dohan and Lukens; (4) contributions of Stadie and Stetten to fat metabolism and to the knowledge of the conversion of carbohydrates to fat; (5) use of isotopes in intermediate carbohydrate metabolism; (6) disappearance of diabetic coma and the importance of truly large amounts of insulin in the first few hours of treatment; (7) replacement of coma as a cause of death by arteriosclerosis in its various forms, and (8) discovery of alloxan diabetes.

This author would be the first to build on these developments. All would welcome a