[Skip to Content]
[Skip to Content Landing]
July 21, 1962

Serum Lipid and Fat Tolerance Determinations in Patients Receiving Sippy Diets

Author Affiliations


JAMA. 1962;181(3):260-262. doi:10.1001/jama.1962.03050290082017b

EVER SINCE the high fat Sippy diet was first introduced in 1915 for the treatment of peptic ulcer, numerous clinical studies have attested to the rationale of this form of therapy in patients with active symptomatology. During recent times much evidence has accumulated which tends to align coronary atherosclerosis with the dietary intake of fats, particularly of the saturated variety. This, plus statistical data showing an increased incidence of myocardial infarctions in ulcer patients who have been treated with Sippy diets now make it necessary to reappraise this treatment in terms of its possible deleterious implications.

The present study was undertaken to obtain more definitive information as to the specific effects of a Sippy feeding regimen on the serum lipids and fat tolerance.

Methods and Material Sixteen consecutive hospitalized patients having active duodenal ulcers, and 5 normal volunteers were selected for investigation (Table 1). In half of the ulcer group,

Sippy, B. W.:  Gastric and Duodenal Ulcer: Medical Cure by Efficient Removal of Gastric Juice Corrosion ,  JAMA 64:1625, 1915.Crossref
Page, I. H., et al.:  Atherosclerosis and Fat Content of Diet ,  Circulation 16:163, 1957.Crossref
 Foods and Nutrition: Symposium on Fats in Human Nutrition ,  JAMA 164:1890, 1957.
Katz, L.; Stamler, J.; and Pick, R.:  Nutrition and Atherosclerosis , Philadelphia: Lea & Febiger, 1958.
Portman, O. W., and Stare, F. J.:  Dietary Regulation of Serum Cholesterol Levels ,  Phys Rev 39:407, 1959.
Goldsmith, G. A.:  Highlights on Cholesterol-Fats, Diets and Atherosclerosis Problem ,  JAMA 176:783, 1961.Crossref
Morrison, L. M.:  Increased Incidence of Coronary Thrombosis in Chronic Peptic Ulcer ,  Rev Gastroenterology 18:313, 1951.
Morris, J. N., and Crawford, M. D.:  Coronary Heart Disease and Physical Activity of Work ,  Brit Med J 2:1458, 1958.Crossref
Briggs, R. D., et al.:  Myocardial Infarction in Patients Treated with Sippy and other High-milk Diets ,  Circulation 21:538, 1960.Crossref
Sandweiss, D. J., et al.:  Do Patients with Peptic Ulcer Have Increased Risk of Premature Death from Arteriosclerotic (Coronary) Heart Disease?  J Mich Med Soc 59:1693, 1960.
Van Handel, E., and Zilversmit, D. B.:  Micromethod for Direct Determination of Serum Triglycerides ,  J Lab Clin Med 50:152, 1957.
Likoff, W., et al.:  Radioactive Fat Absorptive Patterns: Their Significance in Coronary Artery Atherosclerosis ,  Circulation 18:1118, 1958.Crossref
Berkowitz, D., et al.:  Blood Absorption Patterns of Isotopically Labeled Fat and Fatty Acid ,  Ann Intern Med 50:247, 1959.Crossref
Berkowitz, D.; Sklaroff, D.; and Likoff, W.:  Radioactive Fat Absorption Patterns in Geriatric Patient ,  J Amer Geriat Soc 7:941, 1959.
Berkowitz, D., et al.:  Radioactive Fat Tolerance Studies in Coronary Artery Disease ,  Southern Med J 53: 468, 1960.Crossref