[Skip to Content]
Sign In
Individual Sign In
Create an Account
Institutional Sign In
OpenAthens Shibboleth
Purchase Options:
[Skip to Content Landing]
September 8, 1962

Coexisting Heart Disease, Sclerema Neonatorum, and Possible Protozoan Infection: Report of a Case

Author Affiliations

Temple, Tex.

JAMA. 1962;181(10):899-901. doi:10.1001/jama.1962.03050360085019a

IN 1955, Barr reported the first case of interstitial plasmacellular pneumonia to be described outside of the European continent. Barr considered this condition to be of protozoan origin, and he based his opinion on the work of Vanek and Jirovec. Since Barr's paper was published, several instances of this disease have been reported in the American literature.

Report of a Case

From the histologie characteristics, the infant in our case apparently had a protozoan disease. The disease, rather than being localized to the lungs, was generalized, and sclerema neonatorum and congenital heart disease were associated. Congenital anomalies have been described in association with this disease; however, a coexisting sclerema neonatorum has not been mentioned.

Clinical History.—After an apparently normal and spontaneous birth, a premature boy was placed in an incubator. The period of gestation was estimated to be 40 weeks. At the time of birth, the baby weighed 4 lb.

Barr, H. S.:  Interstitial Plasmacellular Pneumonia Due to Pneumocystis Carinii ,  J Clin Path 8:19-24 ( (Feb.) ) 1955.Crossref
Vanek, J., and Jirovec, O.:  Parasitare Pneumonie, "Interstitielle" Plasmazellenpneumonie der Fruhgeborenen, verursacht durch Pneumocystis Carinii ,  Zentralbl Bakt (Abt. 1) 158:120-127 ( (May 12) ) 1952.
Terry, B. T.:  Improvement in Technic and Results Made in Examining Microscopically by Razor Section Method 2,000 Malignant Tissues ,  J Lab Clin Med 14:519-531 ( (Feb.) ) 1929.
Stinson, J. C.:  Silver Stain for Fresh Tissues of Nervous System ,  Arch Path 70:328-330 ( (Sept.) ) 1960