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March 24, 1962

Polio Vaccination-Reply

Author Affiliations

The Wistar Institute, Philadelphia

JAMA. 1962;179(12):988. doi:10.1001/jama.1962.03050120066020

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To the Editor:—  The title of my article was "Live Poliomyelitis Virus Vaccines," and it is absolutely correct to say that the research goes back to the year 1950. Dr. Kolmer intended to make an inactivated poliomyelitis vaccine by formalizing monkeycord tissue which had been infected with a virulent strain of poliovirus. This is the same principle used by Dr. Salk and has nothing to do with the principle of vaccination with living attenuated virus administered by oral or natural route. Either because of residual living virus in the vaccine or because of inoculation during an epidemic of poliomyelitis, serious mishaps occurred with Dr. Kolmer's vaccine.Turning to more philosophical aspects of priority in scientific discoveries, could Dr. Schneider tell me why the vaccine discovered and developed by me and my associates, Dr. George Jervis and Mr. Thomas Norton, 12 years ago is now called the Sabin vaccine? As one