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The relationship of air pollution to health was studied during a period in the month of November, 1953, when air pollution in New York City reached high levels. An analysis of clinic visits was employed as an index of morbidity at 4 major city hospitals. It disclosed an increase in clinic visits for upper respiratory infections and cardiac illnesses. The increase proved to be statistically significant at 3 of the 4 hospitals for "upper respiratory" visits and 2 of the 4 hospitals for "cardiac," visits. No increase was noted in the number of visits to the asthma clinic. The evidence indicates that morbidity during this air pollution incident was significantly increased.
Greenburg L, Field F, Reed JI, Erhardt CL. Air Pollution and Morbidity in New York City. JAMA. 1962;182(2):161–164. doi:10.1001/jama.1962.03050410057012
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