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May 29, 1967


Author Affiliations

New Haven, Conn

JAMA. 1967;200(9):801. doi:10.1001/jama.1967.03120220103040

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As medical science grows more complex, our specialists tend to become organ-oriented, so that it is difficult to gain an overall perspective of a disease that involves multiple organ systems. Scleroderma is such a disease, and Dr. Marvin Sackner has admirably reviewed its many fascinating manifestations, using as a baseline his personal experience with 65 patients. Dr. Sackner has a special interest in pulmonary physiology, and his discussion of sclerodermatous lung disease represents an outstanding portion of this monograph. Other aspects of the clinical disease are, however, reviewed with balanced wisdom and an evident knowledge of his patients and of the disease in all its manifestations. A bibliography of 516 references attests to the author's careful scholarship and is a valuable feature of this monograph.

Among the things this reviewer learned from this book is that low grade intermittent fever is quite common in scleroderma, occurring in about half the