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November 6, 1967

Human Growth Hormone Levels in Normal Subjects Receiving an Oral Contraceptive

Author Affiliations

From the Department of Obstetrics and Gynecology, University of Minnesota, Minneapolis. Dr. Spellacy and Miss Carlson are now with the Department of Obstetrics and Gynecology, University of Miami, Fla.

JAMA. 1967;202(6):451-454. doi:10.1001/jama.1967.03130190057006

Human growth hormone (HGH) levels were measured by a double antibody radioimmunoassay of plasma from women in both the fasting state, and after insulin-induced hypoglycemia. The tests were performed on 26 normal, ambulatory females'at rest, as a control, and also during the third treatment cycle with a combination-type oral contraceptive. It was found that the oral contraceptive elev[ill] the HGH levels. This would appear to be the mec[ill]m by which oral contraceptives alter carbohydrate metabolism.

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