[Skip to Content]
[Skip to Content Landing]
Article
November 27, 1967

Löffler's Pneumonia Terminating in Fatal Periarteritis Nodosa

Author Affiliations

From the departments of pathology and medicine, Springfield (Mass), Hospital.

JAMA. 1967;202(9):867-869. doi:10.1001/jama.1967.03130220055008
Abstract

This patient apparently made a complete recovery from Löffler's pneumonia in 1957, but several months later began to have recurrent symptoms of wheezing and eosinophilia without further evidence of pulmonary infiltration. These occurrences were increasingly frequent during the ensuing four years, but they were always fairly mild. The persistent eosinophilia, the development of wheezing, the recurrent illnesses at closer and closer intervals, and finally the development of arthralgia, fever, neuritis, and vasculitis indicate that the original Löffler's pneumonia was related to the final fatal disease of periarteritis nodosa. This report indicates that Löffler's pneumonia is not invariably a bland disorder, but rather that it requires long-term follow-up, and possibly long-term treatment, in all cases.

References
1.
Knowles, J.H.: " Miscellaneous Disorders of the Lung ." in Harrison, T.R., et al (eds.):  Principles of Internal Medicine , ed 5, New York: McGraw-Hill Book Co.. Inc.. 1966, pp 955-958.
2.
Spencer, H.:  Pathology of the Lung, Excluding Pulmonary Tuberculosis , New York: Macmillan Co.. 1962. pp 570-578.
3.
Hennell. H., and Sussman, M.L.:  The Roentgen Features of Eosinophilic Infiltrations in the Lungs ,  Radiology 44:328-334 ( (April) ) 1945.
4.
Bayley, E.C.; Lindberg, D.O.N.; and Baggenstoss. A.H.:  Loeffler's Syndrome: Report of a Case With Pathologic Examination of the Lungs ,  Arch Path 40:376-381 ( (Nov) -Dec) 1945.
5.
Dines, D.E.; and Donoghue, F.E.:  Loeffler's Syndrome: Report of Two Cases ,  JAMA 192:254-255 ( (April 19) ) 1965.Crossref
6.
Arkin, A.:  A Clinical and Pathological Study of Periarteritis Nodosa ,  Amer J Path 6:401-426 ( (July) ) 1930.
7.
Churg, J.; and Strauss, L.:  Allergic Granulomatosis. Allergic Angiitis, and Periarteritis Nodosa ,  Amer J Path 27:277-301 ( (March) -April) 1951.
8.
Rich. A.R.:  The Role of Hypersensitivity in Periarteritis Nodosa ,  Bull Hopkins Hosp 71:123-140 ( (Sept) ) 1942.
9.
Rich. A.R.; and Gregory, J.E.:  The Experimental Demonstration that Periarteritis Nodosa is a Manifestation of Hypersensitivity .  Bull Hopkins Hosp 72:65-88 ( (Feb) ) 1943.
10.
Lovshin, L.L., and Kernohan, J.W.:  Peripheral Neuritis in Periarteritis Nodosa: A Clinicopathologic Study ,  Mayo Clin Proc 24:48-52 ( (Jan 19) ) 1949.
11.
Anderson, W.A.D.:  Pathology , ed 5, St. Louis: C. V. Mosby Co., 1966, vol 1. pp 576-579.
12.
Tumulty, P.A.: " Polyarteritis Nodosa ," in Harrison, T. R. et al (eds.):  Principles of Internal Medicine , ed 5. New York: McGraw-Hill Book Co., Inc., 1966, pp 1366-1369.
13.
Sweeney. A.R., and Baggenstoss, A.H.:  Pulmonary Lesions of Periarteritis Nodosa ,  Mayo Clin Proc 24:35-43 ( (Jan 19) ) 1949.
14.
Moskowitz, R.W.; Baggenstoss, A.H.; and Slocumb, C.H.:  Histologic Classification cf Periarteritis Nodosa: A Study of 56 Cases Confirmed at Necropsy ,  Mayo Clin Proc 38:345-357 ( (Aug 14) ) 1963.
×