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Recent data from randomized trials have provided a clear understanding of the effectiveness and safety of differing long-term anticoagulant therapies for proximal vein thrombosis. An issue that has not been addressed is their cost-effectiveness. We have performed a cost-effectiveness analysis to rank alternative approaches for long-term therapy. Less intense oral anticoagulant therapy using warfarin sodium is the most cost-effective approach and is preferred in the majority of patients.
Hull RD, Raskob GE, Hirsh J, Sackett DL. A Cost-effectiveness Analysis of Alternative Approaches for Long-term Treatment of Proximal Venous Thrombosis. JAMA. 1984;252(2):235–239. doi:10.1001/jama.1984.03350020037022
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