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Article
February 10, 1912

THE JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

JAMA. 1912;LVIII(6):412-415. doi:10.1001/jama.1912.04260020096014
Abstract

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SATURDAY, FEBRUARY 10, 1912

A NEW THEORY OF THE COAGULATION OF THE BLOOD  The coagulation phenomena of the blood concern the internist and the surgeon in a variety of practical ways. The stoppage of hemorrhage, the production of intravascular clots leading to thrombosis, the non-coagulability of the blood in certain diseases, with its attendant consequences, are a few familiar instances of the problems which daily arise for consideration in this connection. Despite the enormous amount of attention which has been devoted to the theoretic aspects of the question, physiologists have been unable to agree on any approximately adequate solution. One by one the investigators have pointed out additional factors which have served only to increase the complexity of the situation. Any one who attempts to study the literature of the subject of the coagulation of the blood in an up-to-date text-book will soon find himself entangled in the meshes of apparently irreconcilable observations, antagonistic facts,

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