[Skip to Content]
[Skip to Content Landing]
January 16, 1967

Chronic Urethrocystitis In Women

Author Affiliations

Peoria, Ill

JAMA. 1967;199(3):221. doi:10.1001/jama.1967.03120030125032

To the Editor:—  In "Treatment of the Urethral Syndrome in Women" (184:984, 1963), Robert Zufall, MD, described a group of patients with urinary frequency, dysuria, and other symptoms of inflammation of the lower urinary tract in whom corroborative physical and laboratory findings were minimal if not absent altogether. He wrote, "The urethra has been commonly blamed for this syndrome, and many experienced observers find urethral stenosis, edema, hyperemia, granularity, polyps at the neck of the bladder, or exudate on the trigone," but noted himself, "For the majority of patients in this series, diligent search revealed nothing at all different from the urethras, bladder necks, and trigones of patients who were cystoscoped for unrelated conditions, who had no 'urethral' symptoms." About one third of his patients improved for more than 12 weeks with any form of treatment tried, including intramuscular injections of sterile water.To determine quantitatively whether or not

Streitz, J.M.:  Squamous Epithelium in the Human Trigone ,  J Urol 90:60-66 ( (July) ) 1963.
Ney, C., and Ehrlich, J.C.:  Squamous Epithelium in the Trigone of the Human Female Urinary Bladder ,  J Urol 73:809-819 ( (May) ) 1955.
Clarke, B.G., and Gherardi, G.L.:  Urethrotrigonitis or Epidermidization of the Trigone of the Bladder: A Histologic, Bacteriologic and Clinical Study ,  J Urol 87:545-548 ( (April) ) 1962.
Lintgen, C., and Herbut, P.A.:  A Clinicopathological Study of 100 Female Urethras ,  J Urol 55:298-305 ( (March) ) 1946.
Huffman, J.W.:  The Detailed Anatomy of the Paraurethral Ducts in the Adult Human Female ,  Amer J Obstet Gynec 55:86-100 ( (Jan) ) 1948.
Powell, N.B., and Powell, E.B.:  The Female Urethra: A Clinico-pathological Study ,  J Urol 61:557-567 ( (March) ) 1949.