This randomized clinical trial evaluates whether helmet noninvasive ventilation compared with usual respiratory support reduces mortality in patients with acute hypoxemic respiratory failure due to COVID-19 pneumonia.
These randomized clinical trials assess the effect of roflumilast cream, 0.3%, compared with vehicle cream on clinical status at 8 weeks among patients with chronic plaque psoriasis.
This randomized clinical trial compares the effect of intravenous infusions of tocilizumab vs placebo on patients with polymyalgia rheumatica who were receiving glucocorticoid therapy.
This cohort study examines the validity of the Kidney Donor Profile Index’s hepatitis C virus (HCV) penalty during the direct-acting antiviral era by comparing 5-year allograft survival between recipients of kidneys from HCV-RNA–positive donors vs HCV-RNA–negative donors.
This study investigates whether resistance-associated mutations develop after treatment with sotrovimab in high-risk patients infected with the SARS-CoV-2 Omicron variant.
This Special Communication describes Medicaid eligibility, enrollment, and spending as well as examines areas of Medicaid policy, Medicaid expansion, racial and ethnic health disparities, and the potential to achieve health equity.
This Viewpoint concludes the series on diagnostic excellence and explores the future of diagnostics that emphasize prediction of future health state rather than identification of current disease.
This Viewpoint describes the provisions and limitations of prescription drug pricing reforms enacted by US Congress as part of the Inflation Reduction Act in August 2022.
This Viewpoint from FDA Commissioner Robert Califf, MD, emphasizes the agency’s overarching priorities focused on helping to create a system that benefits from abundant high-quality evidence in a transparent environment.
In this narrative medicine essay, a pediatrician describes his lingering questions about the care his daughter received during her very brief life while he was barred from operating room and compares it to being present when another daughter experienced a stressful birth.
An 18-year-old woman had a 14-year history of recurrent skin, nail, and oral mucosal abnormalities, treated with 3- to 6-month courses of itraconazole; the abnormalities typically recurred within 6 to 12 months of discontinuing itraconazole. Skin scrapings from the lower extremities demonstrated fungal elements; fungal culture of the skin scrapings grew Candida albicans. What is the diagnosis and what would you do next?
This Medical News article discusses the first reported instance of polio in the US since 2013.
This Medical News article discusses recent European reports of asymptomatic monkeypox virus infections.
This Medical News feature examines whether the newly authorized Novavax COVID-19 vaccine will spur unvaccinated holdouts to finally get immunized.
This Arts and Medicine feature describes use of improvisational theater techniques to train health care workers to have persuasive and respectful conversations with vaccine-hesitant patients about accepting COVID-19 vaccination.
This Appendix presents data derived from the 2021-2022 Liaison Committee on Medical Education Annual Medical School Questionnaire-Part II.
This Appendix presents 2021 National GME Census data detailing the numbers and types of ACGME-accredited training programs and the residents and fellows in them.
This JAMA Patient Page describes the combination medication tixagevimab-cilgavimab, which is used to help prevent COVID-19 infection in people with immunosuppression or who have had a COVID-19 vaccine reaction.