October 27, 2010, Vol 304, No. 16, Pages 1749-1856

This Week in JAMA

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JAMA. 2010;304(16):1749. doi:10.1001/jama.2010.1545

Audio Editors' Summary: JAMA: 2010-10-27, Vol. 304, No. 16, This Week's Audio Commentary

A Piece of My Mind

Red Sox Cap

Leana S. Wen, MD, MSc

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JAMA. 2010;304(16):1766-1767. doi:10.1001/jama.2010.1532

Original Contribution

Clinician's Corner

Effects of Diet and Physical Activity Interventions on Weight Loss and Cardiometabolic Risk Factors in Severely Obese Adults: A Randomized Trial

Bret H. Goodpaster, PhD; James P. DeLany, PhD; Amy D. Otto, PhD; et al.

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JAMA. 2010;304(16):1795-1802. doi:10.1001/jama.2010.1505

Editorial
The State of Obesity and Obesity Research
Donna H. Ryan, MD; Robert Kushner, MD, MS

Effect of a Free Prepared Meal and Incentivized Weight Loss Program on Weight Loss and Weight Loss Maintenance in Obese and Overweight Women: A Randomized Controlled Trial

Cheryl L. Rock, PhD, RD; Shirley W. Flatt, MS; Nancy E. Sherwood, PhD; et al.

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JAMA. 2010;304(16):1803-1810. doi:10.1001/jama.2010.1503

Editorial
Treatment Options for Obesity: Do Commercial Weight Loss Programs Have a Role?
Rena R. Wing, PhD

Association of KRAS p.G13D Mutation With Outcome in Patients With Chemotherapy-Refractory Metastatic Colorectal Cancer Treated With Cetuximab

Wendy De Roock, MD; Derek J. Jonker, MD; Federica Di Nicolantonio, PhD; et al.

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JAMA. 2010;304(16):1812-1820. doi:10.1001/jama.2010.1535

Editorial

The Lingering Consequences of Sepsis: A Hidden Public Health Disaster?

Derek C. Angus, MD, MPH

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JAMA. 2010;304(16):1833-1834. doi:10.1001/jama.2010.1546

The State of Obesity and Obesity Research

Donna H. Ryan, MD; Robert Kushner, MD, MS

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JAMA. 2010;304(16):1835-1836. doi:10.1001/jama.2010.1531

Treatment Options for Obesity: Do Commercial Weight Loss Programs Have a Role?

Rena R. Wing, PhD

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JAMA. 2010;304(16):1837-1838. doi:10.1001/jama.2010.1529

Clopidogrel and the Reduced-Function CYP2C19 Genetic Variant: A Limited Piece of the Overall Therapeutic Puzzle

Valentin Fuster, MD, PhD; Joseph M. Sweeny, MD

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JAMA. 2010;304(16):1839-1840. doi:10.1001/jama.2010.1566

Review

Reduced-Function CYP2C19 Genotype and Risk of Adverse Clinical Outcomes Among Patients Treated With Clopidogrel Predominantly for PCI: A Meta-analysis

Jessica L. Mega, MD, MPH; Tabassome Simon, MD, PhD; Jean-Philippe Collet, MD, PhD; et al.

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JAMA. 2010;304(16):1821-1830. doi:10.1001/jama.2010.1543

Editorial
Clopidogrel and the Reduced-Function CYP2C19 Genetic Variant: A Limited Piece of the Overall Therapeutic Puzzle
Valentin Fuster, MD, PhD; Joseph M. Sweeny, MD

Caring for the Critically Ill Patient

Long-term Cognitive Impairment and Functional Disability Among Survivors of Severe Sepsis

Theodore J. Iwashyna, MD, PhD; E. Wesley Ely, MD, MPH; Dylan M. Smith, PhD; et al.

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JAMA. 2010;304(16):1787-1794. doi:10.1001/jama.2010.1553

Medical News & Perspectives

State, Federal Efforts Under Way to Identify Children With “Bubble Boy Syndrome”

Bridget M. Kuehn

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JAMA. 2010;304(16):1771-1773. doi:10.1001/jama.2010.1485

Oversight of Fast-Track Drug Approval by FDA Stuck in Low Gear, Critics Say

Mike Mitka

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JAMA. 2010;304(16):1773-1775. doi:10.1001/jama.2010.1486

Reports of Concussions From Youth Sports Rise Along With Awareness of the Problem

Mike Mitka

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JAMA. 2010;304(16):1775-1776. doi:10.1001/jama.2010.1487

National Children’s Study Expands

Bridget M. Kuehn

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JAMA. 2010;304(16):1776. doi:10.1001/jama.2010.1502

News From the Centers for Disease Control and Prevention

Estimates of Deaths Associated With Seasonal Influenza—United States, 1976-2007

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JAMA. 2010;304(16):1778-1780. doi:

Proportion of Workers Who Were Work-Injured and Payment by Workers’ Compensation Systems—10 States, 2007

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JAMA. 2010;304(16):1780-1782. doi:

Health Agencies Update

AIDS Benefits

Bridget M. Kuehn

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JAMA. 2010;304(16):1777. doi:10.1001/jama.2010.1488

Egg Inspections Slated

Bridget M. Kuehn

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JAMA. 2010;304(16):1777. doi:10.1001/jama.2010.1489

Pharmacogenetics Resources

Bridget M. Kuehn

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JAMA. 2010;304(16):1777. doi:10.1001/jama.2010.1490

Regulation for e-Cigarettes

Bridget M. Kuehn

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JAMA. 2010;304(16):1777. doi:10.1001/jama.2010.1491

Letters

Effects of Folic Acid Plus Vitamin B₁₂vs Placebo in Myocardial Infarction Survivors

Joel B. Mason, MD; John A. Baron, MD

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JAMA. 2010;304(16):1783-1784. doi:10.1001/jama.2010.1473

Effects of Folic Acid Plus Vitamin B₁₂vs Placebo in Myocardial Infarction Survivors—Reply

Jane Armitage, FRCP; Robert Clarke, FRCP; Rory Collins, FRCP

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JAMA. 2010;304(16):1783-1784. doi:10.1001/jama.2010.1474

Long-term Nonprogressive Disease Among Individuals With Untreated HIV Infection

Geoffrey S. Gottlieb, MD, PhD; Robert A. Smith, PhD; Papa Salif Sow, MD, MSc

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JAMA. 2010;304(16):1784-1786. doi:10.1001/jama.2010.1475

Long-term Nonprogressive Disease Among Individuals With Untreated HIV Infection

Mohammad Sajadi, MD; Robert R. Redfield, MD

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JAMA. 2010;304(16):1784-1786. doi:10.1001/jama.2010.1476

Long-term Nonprogressive Disease Among Individuals With Untreated HIV Infection—Reply

Stephen A. Migueles, MD; Mark Connors, MD

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JAMA. 2010;304(16):1784-1786. doi:10.1001/jama.2010.1477

Vaccination Mandates vs Opt-Out Programs and Rates of Influenza Immunization

Robert M. Rakita, MD; Beverly A. Hagar, BSN; Joyce K. Lammert, MD, PhD

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JAMA. 2010;304(16):1786. doi:10.1001/jama.2010.1478

Vaccination Mandates vs Opt-Out Programs and Rates of Influenza Immunization—Reply

Gretchen B. Chapman, PhD

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JAMA. 2010;304(16):1786. doi:10.1001/jama.2010.1479

The Cover

Glimmer of Violence

Janet M. Torpy, MD

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JAMA. 2010;304(16):1753. doi:10.1001/jama.2010.1331

Poetry and Medicine

The Geriatrician Ages

Bill Griffin, MD

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JAMA. 2010;304(16):1754. doi:10.1001/jama.2010.1349

JAMA Patient Page

Sepsis

Huan J. Chang, MD, MPH; Cassio Lynm, MA; Richard M. Glass, MD

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JAMA. 2010;304(16):1856. doi:10.1001/jama.304.16.1856

Commentary

The End of the Quality Improvement Movement: Long Live Improving Value

Robert H. Brook, MD, ScD

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JAMA. 2010;304(16):1831-1832. doi:10.1001/jama.2010.1555

JAMA 100 Years Ago

THE RELATION OF HEREDITY TO CANCER

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JAMA. 2010;304(16):1847. doi:10.1001/jama.2010.1508

Book and Media Reviews

Conn’s Current Therapy 2010

Marshall Godwin, MD

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JAMA. 2010;304(16):1841. doi:10.1001/jama.2010.1547

Trauma Anesthesia

Joseph H. McIsaac, MD, MS

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JAMA. 2010;304(16):1841-1843. doi:10.1001/jama.2010.1548

Infectious Diseases of the Female Genital Tract

Kimberly D. Gregory, MD, MPH

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JAMA. 2010;304(16):1843-1844. doi:10.1001/jama.2010.1549

Children’s Orthopaedics and Fractures

Norman Y. Otsuka, MD

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JAMA. 2010;304(16):1844. doi:10.1001/jama.2010.1550

Echocardiography in Pediatric and Adult Congenital Heart Disease

Martin St. John Sutton, MD, FRCP

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JAMA. 2010;304(16):1844-1845. doi:10.1001/jama.2010.1551

Biology Is Technology: The Promise, Peril, and New Business of Engineering Life

Robert Root-Bernstein, PhD

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JAMA. 2010;304(16):1845-1846. doi:10.1001/jama.2010.1552

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October 27, 2010, Vol 304, No. 16, Pages 1749-1856

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