The Methodology Committee of the Patient-Centered Outcomes Research Institute reports on the process of developing standards to support the validity and generalizability of research as well as patient-centeredness in comparative effectiveness research.
In a retrospective cohort analysis of 4168 patients with advanced non–small cell lung cancer, Zhu and colleagues examined whether adding bevacizumab to chemotherapy with carboplatin and paclitaxel resulted in improved patient survival.
In an analysis of data from 223 475 adults with major trauma, Galvagno and coauthors assessed the association between the use of helicopter and ground emergency services transportation to level I or level II trauma centers and survival.
In a study of men with prostate cancer who received radiation treatment, Sheets et al used the Surveillance, Epidemiology, and End Results database to examine the comparative morbidity and disease control of intensity-modulated radiation therapy, proton therapy, and conformal radiation therapy.
To compare long-term outcomes after open vs endovascular repair of abdominal aortic aneurysm, Jackson and coauthors analyzed data from 4529 Medicare beneficiaries who had undergone isolated repair of intact abdominal aortic aneurysm.
In a retrospective cohort study of 7138 Medicare beneficiaries with early-stage kidney cancer, Tan and coauthors examined overall and kidney cancer–specific survival after patients underwent partial or radical nephrectomy.
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